Old Dominion vs. Georgia Southern Prediction, Odds, Picks - November 22, 2025

Updated Nov. 22, 2025 9:04 a.m. ET

Data Skrive

Oddsmakers heavily favor the Old Dominion Monarchs (7-3) when they visit the Georgia Southern Eagles (5-5) on Saturday, November 22, 2025 in a matchup between Sun Belt foes at Allen E. Paulson Stadium. Old Dominion is favored by 10.5 points. The contest's point total is set at 63.5.

In their last game, the Monarchs won versus the Troy Trojans, 33-0. The Eagles' most recent contest was versus the Coastal Carolina Chanticleers, and they won by a score of 45-40.

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Old Dominion vs. Georgia Southern Game Information & Odds

When: Saturday, November 22, 2025 at 1 p.m. ET
Location: Allen E. Paulson Stadium in Statesboro, Georgia
TV: ESPN+
Live Box Score on FOX Sports

Old Dominion vs Georgia Southern Betting Information updated as of November 22, 2025, 8:45 a.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Old Dominion	-10.5 (-110)	-415	+318	63.5	-108	-122

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Old Dominion vs. Georgia Southern Prediction

Pick ATS: Old Dominion (-10.5)
Pick OU: Under (63.5)
Prediction: Old Dominion 35, Georgia Southern 24

Predictions are made by the Data Skrive betting model.

Learn more about the Old Dominion Monarchs vs. the Georgia Southern Eagles game on FOX Sports!

Old Dominion vs. Georgia Southern Betting Insights

Based on the spread and over/under, the implied score for the tilt is Monarchs 37, Eagles 26.
The Monarchs have an 80.6% chance to claim victory in this game based on the moneyline's implied probability. The Eagles hold a 23.9% implied probability.
Old Dominion has won six games against the spread this season, while failing to cover four times.
Georgia Southern is 5-4-1 ATS this season.

Old Dominion vs. Georgia Southern: Head-to-Head

In their past three head-to-head bouts, Old Dominion has defeated Georgia Southern two times.
In those contests versus Georgia Southern, the Monarchs have covered two times while eclipsing the total on one occasion.
Georgia Southern has been outscored by 26 points in its last three tilts against Old Dominion.

Old Dominion vs. Georgia Southern: 2025 Stats Comparison

	Old Dominion	Georgia Southern
Off. Points per Game (Rank)	32 (42)	30 (57)
Def. Points per Game (Rank)	21.1 (34)	34.6 (127)
Turnovers Allowed (Rank)	20 (128)	10 (25)
Turnovers Forced (Rank)	19 (13)	13 (57)

Old Dominion 2025 Key Players

Name	Position	Stats
Colton Joseph	QB	2,378 YDS (60.8%) / 20 TD / 9 INT 713 RUSH YDS / 11 RUSH TD / 71.3 RUSH YPG
Tre' Brown III	WR	34 REC / 735 YDS / 4 TD / 73.5 YPG
Na'eem Abdul-Rahim Gladding	WR	41 REC / 557 YDS / 6 TD / 55.7 YPG
Trequan Jones	RB	624 YDS / 5 TD / 69.3 YPG / 8.1 YPC
Jeremy Mack Jr.	LB	29 TKL / 4 TFL / 4.5 SACK / 1 INT
Jerome Carter	DB	41 TKL / 1 TFL / 3 INT / 3 PD
Seth Naotala	LB	39 TKL / 3 TFL / 2.5 SACK
Jackson Forrest	LB	25 TKL / 1 TFL / 3.5 SACK

Georgia Southern 2025 Key Players

Name	Position	Stats
JC French	QB	2,293 YDS (62.8%) / 17 TD / 7 INT 232 RUSH YDS / 6 RUSH TD / 23.2 RUSH YPG
Camden Brown	WR	51 REC / 872 YDS / 12 TD / 87.2 YPG
OJ Arnold	RB	884 YDS / 5 TD / 88.4 YPG / 6.8 YPC 15 REC / 194 REC YDS / 1 REC TD / 24.3 REC YPG
Dalen Cobb	WR	52 REC / 470 YDS / 3 TD / 47 YPG
MJ Stroud	DL	19 TKL / 9 TFL / 5.5 SACK
Ayden Jackson	DB	45 TKL / 1 TFL / 2 INT / 2 PD
Brandon Tyson	LB	44 TKL / 1 TFL / 1 INT / 1 PD
Justin Meyers	DB	48 TKL / 0 TFL