Ohio State vs. Northwestern Prediction, Odds, Picks - November 16, 2024

Updated Nov. 16, 2024 9:13 a.m. ET

Data Skrive

A pair of the nation's strongest rushing defenses square off when the No. 2 Ohio State Buckeyes (8-1) take college football's fifth-ranked rushing defense into a matchup with the Northwestern Wildcats (4-5), who have the No. 15 rushing defense, on Saturday, November 16, 2024. The Buckeyes are double-digit, 28-point favorites. The over/under is 44.5 in this game.

Last time out, the Buckeyes defeated the Purdue Boilermakers, with 45-0 being the final score. The Wildcats won against the Purdue Boilermakers in their last game, 26-20.

Keep up with college football all season on FOX Sports.

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Ohio State vs. Northwestern Game Information & Odds

When: Saturday, November 16, 2024 at 12 p.m. ET
Location: Wrigley Field in Chicago, Illinois
TV: BTN
Live Box Score on FOX Sports

More College Football Predictions

Ohio State vs Northwestern Betting Information updated as of November 16, 2024, 8:46 a.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Ohio State	-28 (-110)	-11111	+2208	44.5	-110	-110

Ohio State vs. Northwestern Prediction

Pick ATS: Northwestern (+28)
Pick OU: Over (44.5)
Prediction: Ohio State 34, Northwestern 11

Predictions are made by the Data Skrive betting model.

Learn more about the Ohio State Buckeyes vs. the Northwestern Wildcats game on FOX Sports!

Ohio State vs. Northwestern Betting Insights

Per the spread and over/under, the implied score for the matchup is Buckeyes 36, Wildcats 8.
The Buckeyes have a 99.1% chance to claim victory in this game based on the moneyline's implied probability. The Wildcats have a 4.3% implied probability.
Ohio State is 5-4-0 ATS this season.
Northwestern has won three games against the spread this season, failing to cover six times.

Ohio State vs. Northwestern: 2024 Stats Comparison

	Ohio State	Northwestern
Off. Points per Game (Rank)	38.6 (14)	19.2 (123)
Def. Points per Game (Rank)	10.7 (2)	21.9 (36)
Turnovers Allowed (Rank)	8 (17)	11 (42)
Turnovers Forced (Rank)	13 (57)	13 (57)

Ohio State 2024 Key Players

Name	Position	Stats
Will Howard	QB	2,237 YDS (74%) / 22 TD / 5 INT 128 RUSH YDS / 6 RUSH TD / 14.2 RUSH YPG
Jeremiah Smith	WR	45 REC / 765 YDS / 9 TD / 85 YPG
Quinshon Judkins	RB	647 YDS / 6 TD / 71.9 YPG / 6.1 YPC 12 REC / 94 REC YDS / 1 REC TD / 10.4 REC YPG
Emeka Egbuka	WR	47 REC / 587 YDS / 8 TD / 65.2 YPG
J.T. Tuimoloau	DL	23 TKL / 6 TFL / 5 SACK
Sonny Styles	DB	40 TKL / 4 TFL / 2 SACK
Cody Simon	LB	35 TKL / 5 TFL / 2.5 SACK
Lathan Ransom	DB	30 TKL / 4 TFL / 1 INT / 1 PD

Northwestern 2024 Key Players

Name	Position	Stats
Cam Porter	RB	386 YDS / 6 TD / 42.9 YPG / 4 YPC 18 REC / 127 REC YDS / 0 REC TD / 15.9 REC YPG
Jack Lausch	QB	1,120 YDS (53.6%) / 5 TD / 4 INT 218 RUSH YDS / 1 RUSH TD / 24.2 RUSH YPG
A.J. Henning	WR	40 REC / 426 YDS / 3 TD / 47.3 YPG
Joseph Himon II	RB	230 YDS / 2 TD / 25.6 YPG / 5.2 YPC 13 REC / 91 REC YDS / 1 REC TD / 11.4 REC YPG
Mac Uihlein	LB	58 TKL / 4 TFL / 2 SACK
Theran Johnson	DB	44 TKL / 2 TFL / 2 INT / 3 PD
Xander Mueller	LB	41 TKL / 3 TFL / 1 SACK
Robert Fitzgerald	DB	32 TKL / 0 TFL / 1 INT / 1 PD