James Madison vs. Liberty Prediction, Odds, Picks - September 20, 2025

Updated Sep. 20, 2025 3:04 p.m. ET

Data Skrive

The Liberty Flames (1-2) are 7.5-point underdogs heading into their matchup on Saturday, September 20, 2025 against the James Madison Dukes (1-1). The game's point total is 46.5.

Against the Louisville Cardinals in their last game, the Dukes lost 28-14. The Flames' most recent game was against the Bowling Green Falcons, and they lost by a score of 23-13.

Keep up with college football all season on FOX Sports.

James Madison vs. Liberty Game Information & Odds

When: Saturday, September 20, 2025 at 3:30 p.m. ET
Location: Williams Stadium (VA) in Lynchburg, Virginia
TV: ESPNU
Live Box Score on FOX Sports

James Madison vs Liberty Betting Information updated as of September 20, 2025, 2:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
James Madison	-7.5 (-110)	-313	+246	46.5	-112	-107

James Madison vs. Liberty Prediction

Pick ATS: Liberty (+7.5)
Pick OU: Under (46.5)
Prediction: James Madison 25, Liberty 20

Predictions are made by the Data Skrive betting model.

Learn more about the James Madison Dukes vs. the Liberty Flames game on FOX Sports!

James Madison vs. Liberty Betting Insights

Based on the spread and over/under, the implied score for the tilt is Dukes 27, Flames 20.
The Dukes have a 75.8% chance to collect the win in this meeting based on the moneyline's implied probability. The Flames hold a 28.9% implied probability.
James Madison has a record of 2-0-0 against the spread this season.
Liberty has not won against the spread this year in three games with a spread.

James Madison vs. Liberty: 2025 Stats Comparison

	James Madison	Liberty
Off. Points per Game (Rank)	29.5 (106)	21.7 (97)
Def. Points per Game (Rank)	19 (30)	21.3 (71)
Turnovers Allowed (Rank)	4 (78)	6 (117)
Turnovers Forced (Rank)	4 (47)	2 (96)

James Madison 2025 Key Players

Name	Position	Stats
Matthew Sluka	QB	50 YDS (66.7%) / 1 TD / 2 INT 113 RUSH YDS / 2 RUSH TD / 56.5 RUSH YPG
Alonza Barnett III	QB	232 YDS (61.7%) / 2 TD / 0 INT 7 RUSH YDS / 1 RUSH TD / 3.5 RUSH YPG
Wayne Knight	RB	101 YDS / 1 TD / 50.5 YPG / 8.4 YPC 6 REC / 43 REC YDS / 0 REC TD / 21.5 REC YPG
Landon Ellis	WR	5 REC / 75 YDS / 1 TD / 37.5 YPG
Jacob Thomas	DB	6 TKL / 0 TFL / 1 SACK / 1 INT
Gannon Weathersby	LB	8 TKL / 1 TFL / 1 SACK
Immanuel Bush	DL	4 TKL / 2 TFL / 1 SACK
Trent Hendrick	LB	8 TKL / 2 TFL

Liberty 2025 Key Players

Name	Position	Stats
Ethan Vasko	QB	726 YDS (59.3%) / 6 TD / 3 INT 90 RUSH YDS / 1 RUSH TD / 30 RUSH YPG
Evan Dickens	RB	244 YDS / 2 TD / 81.3 YPG / 6.4 YPC 3 REC / 49 REC YDS / 1 REC TD / 16.3 REC YPG
Donte Lee Jr.	WR	8 REC / 187 YDS / 3 TD / 62.3 YPG
Julian Gray	RB	65 YDS / 0 TD / 21.7 YPG / 6.5 YPC 6 REC / 88 REC YDS / 1 REC TD / 29.3 REC YPG
CJ Bazile Jr.	DL	9 TKL / 0 TFL / 1.5 SACK
Derrell Farrar	LB	8 TKL / 1 TFL / 1 SACK
Brenton Williams	DL	8 TKL / 1 TFL / 1 SACK
Amarian Williams	DB	6 TKL / 0 TFL / 1 INT / 1 PD