East Carolina vs. Memphis Prediction, Odds, Picks - November 15, 2025

Updated Nov. 15, 2025 3:04 p.m. ET

FOX Sports

The Memphis Tigers (8-2) and the 15th-ranked scoring offense will play the East Carolina Pirates (6-3) and the 15th-ranked scoring defense on Saturday, November 15, 2025. The Pirates are favored by 3 points in the outing. The point total is set at 57.5.

Facing the Charlotte 49ers in their last contest, the Pirates won 48-22. The Tigers lost to the Tulane Green Wave, 38-32, in their last game.

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East Carolina vs. Memphis Game Information & Odds

When: Saturday, November 15, 2025 at 4 p.m. ET
Location: Bagwell Field at Dowdy-Ficklen Stadium in Greenville, North Carolina
TV: ESPNU
Live Box Score on FOX Sports

East Carolina vs Memphis Betting Information updated as of November 15, 2025, 2:46 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
East Carolina	-3 (-112)	-152	+127	57.5	-114	-106

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East Carolina vs. Memphis Prediction

Pick ATS: Memphis (+3)
Pick OU: Under (57.5)
Prediction: East Carolina 29, Memphis 26

Predictions are made by the Data Skrive betting model.

Learn more about the East Carolina Pirates vs. the Memphis Tigers game on FOX Sports!

East Carolina vs. Memphis Betting Insights

Per the spread and over/under, the implied score for the matchup is Pirates 30, Tigers 27.
The Pirates have a 60.3% chance to collect the win in this game per the moneyline's implied probability. The Tigers have a 44.1% implied probability.
East Carolina has won five games against the spread this season, while failing to cover four times.
Memphis has put together an 8-2-0 record against the spread this year.

East Carolina vs. Memphis: Head-to-Head

In their past two head-to-head meetings, East Carolina has taken down Memphis two times.
In their last two matchups, each team has covered one time while both contests outpaced the total.
Memphis has been outpaced by 3 points in its last two tilts versus East Carolina.

East Carolina vs. Memphis: 2025 Stats Comparison

	East Carolina	Memphis
Off. Points per Game (Rank)	33.9 (32)	37.1 (9)
Def. Points per Game (Rank)	17.3 (15)	21.1 (50)
Turnovers Allowed (Rank)	8 (13)	9 (23)
Turnovers Forced (Rank)	13 (46)	17 (16)

East Carolina 2025 Key Players

Name	Position	Stats
Katin Houser	QB	2,469 YDS (66.5%) / 14 TD / 5 INT 111 RUSH YDS / 6 RUSH TD / 12.3 RUSH YPG
Anthony Smith	WR	44 REC / 683 YDS / 4 TD / 75.9 YPG
London Montgomery	RB	534 YDS / 5 TD / 59.3 YPG / 5.3 YPC
Yannick Smith	WR	41 REC / 533 YDS / 5 TD / 59.2 YPG
Ja'Marley Riddle	DB	39 TKL / 2 TFL / 2 INT / 2 PD
Samuel Dankah	DL	32 TKL / 3 TFL / 1.5 SACK
Jasiyah Robinson	DL	16 TKL / 3 TFL / 3.5 SACK
Teagan Wilk	DB	24 TKL / 0 TFL / 1 INT / 1 PD

Memphis 2025 Key Players

Name	Position	Stats
Brendon Lewis	QB	2,186 YDS (71.2%) / 12 TD / 5 INT 516 RUSH YDS / 8 RUSH TD / 51.6 RUSH YPG
Cortez Braham	WR	50 REC / 745 YDS / 7 TD / 74.5 YPG
Gregroy Desrosiers	RB	485 YDS / 7 TD / 60.6 YPG / 5.8 YPC 25 REC / 179 REC YDS / 1 REC TD / 25.6 REC YPG
Sutton Smith	RB	535 YDS / 6 TD / 53.5 YPG / 6 YPC
Sam Brumfield	LB	65 TKL / 11 TFL / 4.5 SACK / 1 INT
Kamari Wilson	DB	51 TKL / 3 TFL / 2 INT / 2 PD
Drue Watts	DB	51 TKL / 8 TFL / 2 SACK
Chris Bracy	DB	43 TKL / 8 TFL / 1 INT / 1 PD