Clemson vs. Troy Prediction, Odds, Picks - September 6, 2025

Updated Sep. 6, 2025 3:04 p.m. ET

Data Skrive

The No. 8 Clemson Tigers (0-1) are overwhelming 30.5-point favorites on Saturday, September 6, 2025 against the Troy Trojans (1-0). The over/under is 51.5 for the game.

Against the LSU Tigers in their last contest, the Tigers lost 17-10. In their last contest, the Trojans won versus the Nicholls State Colonels, 38-20.

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Clemson vs. Troy Game Information & Odds

When: Saturday, September 6, 2025 at 3:30 p.m. ET
Location: Memorial Stadium (Clemson, SC) in Clemson, South Carolina
TV: ACC Network
Live Box Score on FOX Sports

Clemson vs Troy Betting Information updated as of September 6, 2025, 2:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Clemson	-30.5 (-110)	-10000	+2500	51.5	-111	-109

Clemson vs. Troy Prediction

Pick ATS: Troy (+30.5)
Pick OU: Over (51.5)
Prediction: Clemson 42, Troy 14

Predictions are made by the Data Skrive betting model.

Learn more about the Clemson Tigers vs. the Troy Trojans game on FOX Sports!

Clemson vs. Troy Betting Insights

Per the spread and over/under, the implied score for the matchup is Tigers 41, Trojans 10.
The Tigers have a 99.0% chance to claim victory in this contest per the moneyline's implied probability. The Trojans hold a 3.8% implied probability.
Clemson has compiled a 0-1-0 record against the spread this season.
Troy has compiled a 0-1-0 record against the spread this season.

Clemson vs. Troy: 2025 Stats Comparison

	Clemson	Troy
Off. Points per Game (Rank)	10 (120)	38 (47)
Def. Points per Game (Rank)	17 (66)	20 (78)
Turnovers Allowed (Rank)	1 (55)	0 (1)
Turnovers Forced (Rank)	2 (22)	1 (51)

Clemson 2025 Key Players

Name	Position	Stats
Adam Randall	RB	16 YDS / 1 TD / 16 YPG / 3.2 YPC 2 REC / 14 REC YDS / 0 REC TD / 14 REC YPG
Cade Klubnik	QB	230 YDS (50%) / 0 TD / 1 INT
Bryant Wesco Jr.	WR	4 REC / 66 YDS / 0 TD / 66 YPG
T.J. Moore	WR	4 REC / 55 YDS / 0 TD / 55 YPG
Ronan Hanafin	DB	12 TKL / 0 TFL
Sammy Brown	LB	11 TKL / 1 TFL
Wade Woodaz	LB	7 TKL / 2 TFL
Avieon Terrell	DB	6 TKL / 0 TFL

Troy 2025 Key Players

Name	Position	Stats
Will Crowder	QB	144 YDS (58.3%) / 3 TD / 0 INT 43 RUSH YDS / 1 RUSH TD / 43 RUSH YPG
Tae Meadows	RB	186 YDS / 1 TD / 186 YPG / 8.1 YPC 1 REC / 12 REC YDS / 0 REC TD / 12 REC YPG
Roman Mothershed	WR	2 REC / 32 YDS / 1 TD / 32 YPG
Tray Taylor	WR	1 REC / 28 YDS / 1 TD / 28 YPG
Jaquez White	DB	8 TKL / 0 TFL / 1 INT / 1 PD
Devin Lafayette	DB	6 TKL / 1 TFL / 1 SACK
Donnie Smith		3 TKL / 1 TFL / 1 SACK
Jordan Stringer	LB	9 TKL / 1 TFL