Arizona State vs. Mississippi State Prediction, Odds, Picks - September 6, 2025

Updated Sep. 6, 2025 3:04 p.m. ET

Data Skrive

The Mississippi State Bulldogs (1-0) are 6.5-point underdogs heading into their matchup on Saturday, September 6, 2025 against the No. 12 Arizona State Sun Devils (1-0). The point total is set at 58.5.

In their most recent action, the Sun Devils won against the Northern Arizona Lumberjacks, 38-19. Facing the Southern Miss Golden Eagles in their most recent contest, the Bulldogs won 34-17.

Keep up with college football all season on FOX Sports.

Arizona State vs. Mississippi State Game Information & Odds

When: Saturday, September 6, 2025 at 7:30 p.m. ET
Location: Davis Wade Stadium at Scott Field in Starkville, Mississippi
TV: ESPN2
Live Box Score on FOX Sports

Arizona State vs Mississippi State Betting Information updated as of September 6, 2025, 2:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Arizona State	-6.5 (-111)	-241	+196	58.5	-114	-106

Arizona State vs. Mississippi State Prediction

Pick ATS: Arizona State (-6.5)
Pick OU: Under (58.5)
Prediction: Arizona State 38, Mississippi State 19

Predictions are made by the Data Skrive betting model.

Learn more about the Arizona State Sun Devils vs. the Mississippi State Bulldogs game on FOX Sports!

Arizona State vs. Mississippi State Betting Insights

Based on the spread and over/under, the implied score for the matchup is Sun Devils 32, Bulldogs 26.
The Sun Devils have a 70.7% chance to win this contest per the moneyline's implied probability. The Bulldogs hold a 33.8% implied probability.
Arizona State has not won against the spread this season in one opportunities.
Mississippi State has won all one of its games against the spread this season.

Arizona State vs. Mississippi State: 2025 Stats Comparison

	Arizona State	Mississippi State
Off. Points per Game (Rank)	38 (47)	34 (55)
Def. Points per Game (Rank)	19 (77)	17 (66)
Turnovers Allowed (Rank)	1 (55)	1 (55)
Turnovers Forced (Rank)	1 (51)	1 (51)

Arizona State 2025 Key Players

Name	Position	Stats
Sam Leavitt	QB	257 YDS (64.1%) / 2 TD / 1 INT 73 RUSH YDS / 2 RUSH TD / 73 RUSH YPG
Jordyn Tyson	WR	12 REC / 141 YDS / 2 TD / 141 YPG
Kyson Brown	RB	73 YDS / 0 TD / 73 YPG / 10.4 YPC 6 REC / 72 REC YDS / 0 REC TD / 72 REC YPG
Raleek Brown	RB	38 YDS / 1 TD / 38 YPG / 7.6 YPC 3 REC / 13 REC YDS / 0 REC TD / 13 REC YPG
Jordan Crook	LB	7 TKL / 1 TFL / 1 SACK
Elijah O'Neal	DL	6 TKL / 1 TFL / 1 SACK
Keith Abney	DB	3 TKL / 1 TFL / 1 SACK
Myles Rowser	DB	4 TKL / 1 TFL

Mississippi State 2025 Key Players

Name	Position	Stats
Da'Marion Bothwell	RB	43 YDS / 2 TD / 43 YPG / 4.3 YPC
Davon Booth	RB	79 YDS / 1 TD / 79 YPG / 4.9 YPC 1 REC / 12 REC YDS / 0 REC TD / 12 REC YPG
Seydou Traore	TE	5 REC / 77 YDS / 1 TD / 77 YPG
Blake Shapen	QB	270 YDS (76.5%) / 1 TD / 1 INT
Brylan Lanier	DB	6 TKL / 0 TFL / 1 INT / 1 PD
Will Whitson	DL	4 TKL / 2 TFL / 1 SACK
Malick Sylla	LB	6 TKL / 0 TFL
Jalen Smith	LB	6 TKL / 0 TFL