Appalachian State vs. Southern Miss Prediction, Odds, Picks - September 13, 2025

Updated Sep. 13, 2025 3:04 p.m. ET

FOX Sports

The Southern Miss Golden Eagles (1-1) are 3.5-point underdogs in a home Sun Belt matchup against the Appalachian State Mountaineers (2-0) on Saturday, September 13, 2025 at M.M. Roberts Stadium. A 56.5-point over/under is set for the contest.

The Mountaineers won against the Lindenwood Lions in their last game, 20-13. In their last contest, the Golden Eagles won versus the Jackson State Tigers, 38-20.

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Appalachian State vs. Southern Miss Game Information & Odds

When: Saturday, September 13, 2025 at 7 p.m. ET
Location: M.M. Roberts Stadium in Hattiesburg, Mississippi
TV: ESPN+
Live Box Score on FOX Sports

Appalachian State vs Southern Miss Betting Information updated as of September 13, 2025, 8:45 a.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Appalachian State	-3.5 (-110)	-172	+144	56.5	-110	-110

Appalachian State vs. Southern Miss Prediction

Pick ATS: Appalachian State (-3.5)
Pick OU: Under (56.5)
Prediction: Appalachian State 30, Southern Miss 18

Predictions are made by the Data Skrive betting model.

Learn more about the Appalachian State Mountaineers vs. the Southern Miss Golden Eagles game on FOX Sports!

Appalachian State vs. Southern Miss Betting Insights

Based on the spread and over/under, the implied score for the matchup is Mountaineers 30, Golden Eagles 26.
The Mountaineers have a 63.2% chance to win this contest per the moneyline's implied probability. The Golden Eagles have a 41.0% implied probability.
Appalachian State has covered once in two chances against the spread this season.
Southern Miss has a record of 1-1-0 against the spread this season.

Appalachian State vs. Southern Miss: 2025 Stats Comparison

	Appalachian State	Southern Miss
Off. Points per Game (Rank)	27 (81)	27.5 (77)
Def. Points per Game (Rank)	12 (35)	27 (93)
Turnovers Allowed (Rank)	5 (122)	1 (22)
Turnovers Forced (Rank)	4 (19)	3 (37)

Appalachian State 2025 Key Players

Name	Position	Stats
AJ Swann	QB	662 YDS (62.5%) / 5 TD / 1 INT 40 RUSH YDS / 0 RUSH TD / 20 RUSH YPG
Rashod Dubinion	RB	305 YDS / 1 TD / 152.5 YPG / 6.5 YPC 6 REC / 34 REC YDS / 0 REC TD / 17 REC YPG
Jaden Barnes	WR	14 REC / 205 YDS / 2 TD / 102.5 YPG
Dalton Stroman	WR	11 REC / 229 YDS / 1 TD / 114.5 YPG
Ja'Den McBurrows	DB	9 TKL / 2 TFL / 1 INT / 1 PD
Thomas Davis	DL	9 TKL / 2 TFL / 1 SACK
Aiden Benton	DL	5 TKL / 1 TFL / 1.5 SACK
Kevin Abrams-Verwayne	DL	7 TKL / 1 TFL / 1.5 SACK

Southern Miss 2025 Key Players

Name	Position	Stats
Braylon Braxton	QB	413 YDS (66.7%) / 5 TD / 1 INT 78 RUSH YDS / 0 RUSH TD / 39 RUSH YPG
Micah Davis	WR	5 REC / 44 YDS / 2 TD / 22 YPG
Jeffery Pittman	RB	87 YDS / 0 TD / 43.5 YPG / 4.6 YPC 7 REC / 54 REC YDS / 0 REC TD / 27 REC YPG
Kadinn Morris	TE	4 REC / 63 YDS / 1 TD / 31.5 YPG
Josh Battle	DB	12 TKL / 1 TFL / 1 SACK
Joshuah Moten	DB	17 TKL / 0 TFL
Michael Montgomery	LB	14 TKL / 0 TFL / 1 INT / 1 PD
JJ Hawkins	DL	6 TKL / 0 TFL / 1 SACK