DePaul vs. Detroit Mercy Prediction, How to Watch, Odds, Channel - Nov 23

Updated Nov. 23, 2025 8:27 p.m. ET

Data Skrive

The Detroit Mercy Titans (1-5) will attempt to break a four-game road losing streak when they take on the DePaul Blue Demons (3-2) on Sunday, November 23, 2025 at Wintrust Arena. The contest airs at 6 p.m. ET on ESPN+.

The Blue Demons enter their game against the Titans as heavy favorites. The Blue Demons are favored by 20.5 points. The game features a point total of 152.5.

Continue scrolling to get the download ahead of placing bets on the DePaul-Detroit Mercy contest.

DePaul vs. Detroit Mercy How to Watch & Odds

When: Sunday, November 23, 2025 at 6 p.m. ET
Where: Wintrust Arena in Chicago, Illinois
TV: ESPN+
Live Box Score: FOX Sports

Blue Demons vs Titans Betting Information
Favorite	Spread	Favorite Spread Odds	Underdog Spread Odds	Total	Over Total Odds	Under Total Odds	Favorite Moneyline	Underdog Moneyline
Blue Demons	-20.5	-109	-111	152.5	-112	-108	-3333	+1350

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DePaul vs. Detroit Mercy Prediction

Pick ATS: Detroit Mercy (+20.5)
Pick OU: Under (152.5)
Prediction: DePaul 84, Detroit Mercy 66

Learn more about the DePaul Blue Demons vs. the Detroit Mercy Titans game on FOX Sports!

DePaul vs. Detroit Mercy Betting Insights

Betting Line Implied Predictions

Based on the spread and over/under, the implied score for the encounter is Blue Demons 86, Titans 66.
The Blue Demons have a 97.1% chance to collect the win in this meeting based on the moneyline's implied probability.
The Titans hold a 6.9% implied probability to win.

Key Spread Facts

DePaul has won three games against the spread this season, while failing to cover twice.
Detroit Mercy has won two games against the spread this season.
DePaul has been favored by 20.5 points or more three times this season, and covered the spread in two of those games.
Detroit Mercy has covered the spread once when an underdog by 20.5 points or more this year (in two opportunities).

Key Total Facts

In three games this season, the Blue Demons and their opponent have combined to score more than 152.5 points.
There have been three Titans games this season with more than 152.5 points scored.
The two teams combine to average 2.4 points per game fewer than the total for this matchup (152.5).

Key Moneyline Facts

DePaul has won three of four games when the moneyline favorite this season (75%).
Detroit Mercy has been the underdog in four games this season, and it has failed to win any of those contests.
DePaul has a record of 3-1 when it has played as a moneyline favorite with odds of -3333 or shorter (winning 75%).
Detroit Mercy has played as an underdog of +1350 or more twice this season and lost both games.

DePaul vs. Detroit Mercy: 2025-26 Stats Comparison

	DePaul	Detroit Mercy
Points Scored Per Game (Rank)	77.8 (204)	72.3 (290)
Points Allowed (Rank)	67 (71)	82.2 (317)
Rebounds (Rank)	10.2 (162)	11.8 (66)
3pt Made (Rank)	7.4 (225)	6.3 (303)
Assists (Rank)	18.6 (42)	12.2 (299)
Turnovers (Rank)	13 (248)	12.3 (204)