Illinois vs. Creighton Prediction, Odds, Picks – Women's Basketball NCAA Tournament First Round 2025

A first-round NCAA Tournament matchup will see the ninth-seeded Creighton Bluejays (26-6) take the court as 1-point underdogs against the No. 8 seed Illinois Fighting Illini (21-9) on Saturday at Moody Center. The contest tips off at 7:15 p.m. ET on ESPNews. Here's what you need to know when filling out your brackets for this 8-9 matchup. The point total in the matchup is set at 136.5.

Illinois vs. Creighton Game Info

• Game day: Saturday, March 22, 2025
• Game time: 7:15 p.m. ET
• TV channel: ESPNews
• Follow this game live on FOX Sports

Illinois vs. Creighton Odds

Illinois vs. Creighton Prediction

• Computer Pick ATS: Creighton (+1)
  
• Computer Pick OU: Under (136.5)
  
• Computer Prediction: Creighton 69, Illinois 65

Learn more about the Illinois Fighting Illini vs. the Creighton Bluejays game on FOX Sports!

Illinois Betting Insights

• The Fighting Illini have 10 wins in 23 games against the spread this year.
• Illinois is 5-12 ATS as 1-point favorites or more.
• Out of 23 Fighting Illini games so far this season, nine have gone over the total.
• Illinois has been the moneyline favorite in 12 games this season and won eight (66.7%) of those contests.
• The Fighting Illini are 8-4 this season when entering a game favored by -118 or more on the moneyline.

Creighton Betting Insights

• The Bluejays' record against the spread is 11-10-0.
• As a 1-point underdog or greater, Creighton has two wins ATS (2-3).
• This year, 13 of the Bluejays' 21 games have hit the over.
• Creighton has been moneyline underdogs in four games this season, however, it has failed to come away with a win in any of those games.
• The Bluejays have won all of their four games in which they were named as at least a -102 moneyline underdog.

Illinois' Top Performers

Creighton's Top Performers

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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Illinois Fighting Illini

Creighton Bluejays