How to Watch Buccaneers vs. 49ers: Time, TV Channel and Live Stream – 2025 Week 6

On Sunday at 4:25 p.m. ET, two of the best offensive players in the NFL will be featured when quarterback Baker Mayfield and the Tampa Bay Buccaneers (4-1) host Christian McCaffrey and the San Francisco 49ers (4-1).

On offense, the Buccaneers rank seventh in the NFL with 27 points per game. Meanwhile, they rank 23rd in points allowed (310.8 points allowed per contest). The 49ers are accumulating 21.2 points per game on offense this season (21st-ranked). Meanwhile, they are allowing 19.6 points per game (sixth-ranked) on defense.

Below we dive into all of the details you need to know about this contest, including how to watch on TV.

Check out the full NFL schedule on FOX Sports! Or visit FOX Sports' NFL hub for everything you need to make the most of this season’s action.

How to Watch Buccaneers vs. 49ers

• When: Sunday, October 12, 2025 at 4:25 p.m. ET
• Where: Raymond James Stadium in Tampa, Florida
• TV: CBS
• Live Box Score: Fox Sports

Learn more about the Tampa Bay Buccaneers vs. the San Francisco 49ers on FOX Sports!

Buccaneers vs. 49ers: Head-to-Head

• Against Tampa Bay, San Francisco has collected four wins over the past five matchups.
• Tampa Bay has scored 40 fewer points than San Francisco in their past five games.

Buccaneers' 2025 Schedule

Buccaneers Stats & Insights

• Offensively, Tampa Bay ranks sixth in the NFL with 243.4 passing yards per game. Meanwhile, the defense ranks 20th in passing yards allowed per contest (218.4).
• The Buccaneers are averaging 110.4 rushing yards per game on offense, which ranks them 22nd in the NFL. On defense, they rank eighth, giving up 92.4 rushing yards per game.
• With four forced turnovers (23rd in NFL) against two turnovers committed (first in NFL), Tampa Bay's +2 turnover margin ranks eighth in the league.

Buccaneers Key Players

• To go along with his 1,283 passing yards and 65.1% completion percentage this season, Mayfield has thrown for 10 touchdowns against one interception.
• In five games in 2025, Emeka Egbuka has been targeted 38 times for 25 catches, 445 yards and five touchdowns.
• Bucky Irving has contributed to the Buccaneers' offense by scampering for 237 yards (59.3 yards per carry) and zero rushing touchdowns.

49ers' 2025 Schedule

49ers Stats & Insights

• San Francisco's pass offense has been excelling, putting up 290.6 passing yards per game (best) this season. Defensively, it ranks 14th by surrendering 207.6 passing yards per game.
• The 49ers rank fifth-worst in rushing yards per game (85.2), but they've been more productive defensively, ranking 15th in the NFL with 108 rushing yards surrendered per contest.
• San Francisco sports a -3 turnover margin this season, which ranks 22nd in the NFL.

49ers Key Players

• In five games, McCaffrey has run for 282 yards (56.4 per game) and zero touchdowns.
• Mac Jones has passed for 905 yards (301.7 per game), completing 66.7% of his throws, with six touchdowns and one interception in three games.
• Jake Tonges has 19 receptions for 166 yards (33.2 per game) and three touchdowns in five games.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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