Colts vs. Dolphins 2025 Prediction, Odds, Picks - Sep 7

The Indianapolis Colts (0-0) are favored by 1.5 points versus the Miami Dolphins (0-0) on September 7, 2025, starting at 1 p.m. ET, airing on CBS. The game has an over/under of 47.5 points.

Keep up with the 2025 NFL season on FOX Sports.

Gronk and Julian Edelman preview Raiders vs. Patriots, Baker Mayfield | FOX NFL Kickoff

Gronk and Julian Edelman previewed Raiders vs. Patriots and spoke on Baker Mayfield during FOX NFL Kickoff.

Colts vs. Dolphins Odds & Betting Lines

Colts vs. Dolphins Prediction & Pick

• Pick ATS: Colts (-1.5)
  
• Pick OU: Under (47.5)
  
• Prediction: Colts 23 - Dolphins 21

How to Watch Indianapolis vs. Miami

• Game date: Sunday, September 7, 2025
• Time: 1 p.m. ET
• Venue: Lucas Oil Stadium
• Location: Indianapolis, Indiana
• TV: CBS
• Live Boxscore: FOX Sports

Colts vs. Dolphins Recent Matchups

• Over their last four meetings, Indianapolis has tallied three wins versus Miami.
• Miami has been outscored by 15 points in its last four tilts against Indianapolis.

Indianapolis Betting Info

• Indianapolis put together a 9-8-0 ATS record last year.
• The Colts' ATS record as 1.5-point favorites or greater was 3-4 last year.
• Last season, the combined scoring went over the point total nine times in Indianapolis games.
• The Colts won five of the seven games they were favored on the moneyline last season (71.4%).
• Indianapolis went 5-2 in games it played as a moneyline favorite with odds of -112 or shorter (71.4%).
• Based on this game's moneyline, the Colts' implied win probability is 52.8%.

Colts Stats (2024)

Indianapolis' Key Players

Offense

• Last year over 14 games, Jonathan Taylor churned out 1,431 rushing yards (fourth in the NFL) and scored 11 rushing touchdowns. He averaged 102.2 yards per game and 4.7 per attempt (11th in the NFL).
• On top of his impact on the ground, Taylor caught 18 passes (on 31 targets) for 136 yards, with one receiving touchdown. He averaged 9.7 yards per game.
• In 11 games, Anthony Richardson had 1,814 passing yards, with eight touchdowns against 12 interceptions and completing 47.7% of his attempts.
• Richardson also had six rushing touchdowns and 499 rushing yards.
• Over the course of 10 games for the Giants last season, Daniel Jones racked up 2,070 passing yards, while throwing eight touchdowns against seven interceptions and completing 63.3% of his attempts.
• He added 265 yards on the ground, while scoring two rushing touchdowns. He averaged 26.5 yards per game and 4 per attempt.
• Alec Pierce had 824 receiving yards and seven touchdowns from 37 receptions on 69 targets.

Defense

• Zaire Franklin's 2024 showing included 173 tackles, 11 TFL, 3.5 sacks, and two interceptions over 17 games.
• Nick Cross had three interceptions on top of 145 tackles, six TFL, one sack, and five passes defended.
• Jaylon Jones had three TFL, 100 tackles, and two interceptions.
• For the Vikings, Camryn Bynum intercepted three passes to go with 96 tackles, two TFL, and 10 passes defended.

Miami Betting Info

• Miami compiled a 7-9-1 ATS record last year.
• As 1.5-point underdogs or greater, the Dolphins went 3-5 against the spread last year.
• A total of eight of Miami's games last year went over the point total.
• The Dolphins were underdogs eight times last season and won twice.
• Miami was 2-6 last season when entering a game as the underdog by -108 or more on the moneyline.
• The bookmakers' moneyline implies a 51.9% chance of a victory for the Dolphins.

Dolphins Stats (2024)

Miami's Key Players

Offense

• Last season in 17 games, De'Von Achane churned out 907 yards rushing and scored six rushing TDs. He averaged 53.4 yards per game and 4.5 per attempt (17th in NFL).
• In addition to his rushing stats, Achane had 78 catches (on 87 targets) for 592 yards, with six receiving TDs. He averaged 34.8 receiving yards per game.
• Tua Tagovailoa had 2,867 passing yards, 19 TD passes and seven INTs. His completion percentage was 72.9% and he averaged 260.6 yards per game and 7.2 per attempt.
• Tyreek Hill put up 959 yards receiving and six TDs on 81 receptions while being targeted 123 times last year.
• For the Titans, Nick Westbrook-Ikhine had 32 catches for 497 yards and nine TDs (ninth in the NFL). He averaged 2.3 yards per game in 14 games and was targeted 60 times.

Defense

• In 2024, Jordyn Brooks amassed three sacks to go along with 11 TFL and 143 tackles over 17 games.
• Tyrel Dodson had two sacks plus five TFL, 107 tackles, and three interceptions.
• Zach Sieler posted 10 sacks in addition to his 13 TFL, 55 tackles, and one interception.
• Minkah Fitzpatrick's production for the Steelers included one INT as well as 96 tackles, one TFL, and four passes defended in 17 games

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

Want great stories delivered right to your inbox?

Create or log in to your FOX Sports account, follow leagues, teams and players to receive a personalized newsletter daily.

FOLLOW Follow your favorites to personalize your FOX Sports experience

Indianapolis Colts

Miami Dolphins