Broncos vs. Titans 2025 Prediction, Odds, Picks - Sep 7

The Denver Broncos (0-0) are favored by 9.5 points against the Tennessee Titans (0-0) on September 7, 2025, starting at 4:05 p.m. ET, airing on FOX. The matchup has an over/under of 42.5 points.

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Broncos vs. Titans Odds & Betting Lines

Broncos vs. Titans Prediction & Pick

• Pick ATS: Broncos (-9.5)
  
• Pick OU: Over (42.5)
  
• Prediction: Broncos 33 - Titans 12

How to Watch Denver vs. Tennessee

• Game date: Sunday, September 7, 2025
• Time: 4:05 p.m. ET
• Venue: Empower Field at Mile High
• Location: Denver, Colorado
• TV: Watch on FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)

Broncos vs. Titans Recent Matchups

• In their past two matchups, Tennessee holds a split 1-1 record against Denver.
• Over their last two head-to-head contests, Denver has racked up 26 points, while Tennessee has posted 17.

Denver Betting Info

• Denver put together a 12-5-0 ATS record last year.
• The Broncos covered every time (2-0) as a 9.5-point favorite or greater last season.
• Last season, 10 Denver games went over the point total.
• The Broncos won all eight of the games they were the moneyline favorite last season.
• Denver played as a moneyline favorite of -441 or shorter in only two games last season, and it won both.
• The Broncos have an 81.5% chance to win this contest based on the moneyline's implied probability.

Broncos Stats (2024)

Denver's Key Players

Offense

• Bo Nix averaged 6.7 passing yards per attempt (27th in the NFL) and 222.1 yards per game last year, completing 66.3% of his passes on the way to 3,775 total yards, 29 touchdowns (sixth in the NFL) and 12 interceptions in 17 games.
• On the ground, Nix added four rushing touchdowns and 430 rushing yards.
• J.K. Dobbins averaged 69.6 rushing yards per contest through 13 games for the Chargers (905 total yards), while scoring nine rushing touchdowns.
• Dobbins also had 32 catches for 153 yards. He was targeted 38 times and averaged 11.8 yards per game.
• Courtland Sutton registered 1,081 receiving yards and eight touchdowns on 81 receptions while being targeted 135 times last year.
• Marvin Mims was targeted 52 times, resulting in 39 catches for 503 yards.

Defense

• Nik Bonitto's 2024 showing included 48 tackles, 16 TFL, 13.5 sacks, and one interception over 17 games.
• Brandon Jones' stats included three interceptions as well as 115 tackles, two TFL, and 10 passes defended.
• During the 2024 campaign, Zach Allen had 61 tackles, 15 TFL, and 8.5 sacks over 16 games.
• Jonathon Cooper totaled 10.5 sacks to go with 11 TFL and 58 tackles in 17 games.

Tennessee Betting Info

• Tennessee covered just twice in 17 matchups with a spread last year.
• The Titans were winless ATS (0-2) when playing as at least 9.5-point underdogs last year.
• Tennessee games went over the point total 10 out of 17 times last year.
• Last season, the Titans won two out of the 12 games, or 16.7%, in which they were the underdog.
• Last season, Tennessee was at least a +340 underdog on the moneyline two times, losing each of those contests.
• The moneyline for this contest implies a 22.7% chance of a victory for the Titans.

Titans Stats (2024)

Tennessee's Key Players

Offense

• Tony Pollard averaged 67.4 yards rushing last season (1,079 total yards) while scoring five rushing TDs.
• Pollard also was a part of the passing game with 238 receiving yards (14.9 per game) on 41 receptions (2.6 per game), targeted 57 times. He did not score a receiving TD.
• Calvin Ridley put together a 2024 campaign that included 64 receptions for 1,017 yards and four receiving TDs in 17 games. He was on the end of 120 targets and averaged 3.8 catches.
• Tyler Lockett totaled 600 yards receiving and two TDs on 49 receptions while being targeted 74 times last season with the Seahawks.
• Chigoziem Okonkwo was targeted 70 times, resulting in 52 receptions for 479 yards.

Defense

• In the 2024 season with the Panthers Xavier Woods put up 119 tackles, two TFL, and three interceptions over 17 games.
• Jeffery Simmons' production included 76 tackles, 11 TFL, five sacks, and four passes defended.
• Cody Barton picked off two passes to go along with 104 tackles, two TFL, 1.5 sacks, and five passes defended during the 2024 campaign for the Broncos.
• Amani Hooker picked off five passes in addition to 70 tackles, four TFL, and nine passes defended. He was sixth in the NFL in interceptions.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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