2025-26 Arizona Cardinals Odds: Odds to win Super Bowl, NFL Playoffs, Division

Updated Dec. 1, 2025 10:30 a.m. ET

Data Skrive

As of Dec. 1 the Arizona Cardinals' odds of winning the Super Bowl are listed at +100000.

The Cardinals squared off against the Tampa Bay Buccaneers in their last game, falling 20-17. Jacoby Brissett led the Cards with 301 yards on 29-of-40 passing (72.5%) for two touchdowns and one interception. Bam Knight totaled 62 rushing yards on 11 carries (5.6 yards per carry). He also had three catches for 36 yards and one touchdown. Trey McBride had eight receptions for 82 yards (10.3 per catch) and one touchdown.

Cardinals Postseason Odds

Odds to win the Super Bowl: +100000 (Bet $100 to win $100,000)

Learn more about the Arizona Cardinals on Fox Sports.

Cardinals Super Bowl Odds Insights

The Cardinals have +100000 odds to win the Super Bowl, which ranks 22nd in the league. Our computer rankings also have them ranked 22nd.
The Cardinals' Super Bowl odds have gotten worse since the preseason, going from +5500 before the season to +100000 currently. That's the third-biggest change in the NFL.
The Cardinals sport a 0.1% chance of winning the Super Bowl, based on their most recent odds (+100000).

Cardinals Betting Insights

The Cardinals have won six games against the spread this season, while failing to cover six times.
A total of seven out of 12 Arizona games this season have gone over the point total.
The Cardinals have gone 2-1 in games they were favored on the moneyline (winning 66.7% of those games).
Arizona has entered the game as an underdog nine times this season and won once.

Cardinals Top Players

Brissett has posted 2,188 passing yards (243.1 per game) with a 67.5% completion percentage (204-for-302) while throwing 13 touchdowns and four interceptions. He also has 116 yards on the ground via 27 attempts and one rushing touchdown.
Knight has churned out a team-leading 255 rushing yards (25.5 per game) and four scores.
Knight is considered questionable for the upcoming game versus the Rams on Sunday.
Emari Demercado has rushed for 241 yards (30.1 per game).
Demercado will not suit up against the Rams, as he has been ruled out.
McBride has 88 catches (on 118 targets) and leads the team with 879 receiving yards (73.3 per game) while scoring eight touchdowns.
Marvin Harrison Jr. has been targeted 69 times and added 594 yards (on 40 catches) plus four touchdowns.
Harrison is considered questionable for the upcoming matchup against the Rams on Sunday.
Michael Wilson is averaging 47.5 yards per game, racking up 50 receptions (78 targets) for 570 yards and one touchdown.
Josh Sweat has notched a team-leading 11.0 sacks, while adding 12.0 TFL and 25 tackles.
Sweat's game status for Sunday's Week 14 matchup against the Rams is currently unknown.
Budda Baker has totaled 87 tackles, 2.0 TFL, 0.5 sacks, and one interception to lead the team in tackles.
This season Dadrion Taylor-Demerson leads the team with two interceptions and has added 34 tackles and five passes defended.
Taylor-Demerson is out for Sunday's matchup versus the Rams.

Cardinals 2025-26 Schedule

Opponent	Week	Date	Opponent Power Ranking	Favorite	Total
@ Saints	1	Sept. 7	29th	Cardinals (-5.5)	44.5
Panthers	2	Sept. 14	18th	Cardinals (-7)	45.5
@ 49ers	3	Sept. 21	4th	49ers (-1.5)	44.5
Seahawks	4	Sept. 25	2nd	Seahawks (-1.5)	43.5
Titans	5	Oct. 5	31st	Cardinals (-7.5)	41.5
@ Colts	6	Oct. 12	5th	Colts (-9.5)	45.5
Packers	7	Oct. 19	12th	Packers (-7)	44.5
@ Cowboys	9	Nov. 3	17th	Cowboys (-3.5)	54.5
@ Seahawks	10	Nov. 9	2nd	Seahawks (-6.5)	45.5
49ers	11	Nov. 16	4th	49ers (-3.5)	48.5
Jaguars	12	Nov. 23	6th	Jaguars (-2.5)	47.5
@ Buccaneers	13	Nov. 30	11th	Buccaneers (-3.5)	44.5
Rams	14	Dec. 7	1st	Rams (-7.5)	48.5
@ Texans	15	Dec. 14	3rd	Texans (-2.5)	45.5
Falcons	16	Dec. 21	21st	Cardinals (-3.5)	46.5
@ Bengals	17	TBD	27th	Bengals (-3.5)	47.5
@ Rams	18	TBD	1st	Rams (-4.5)	45.5