Pistons vs. Trail Blazers Prediction, Odds, Picks - Dec. 22

The Portland Trail Blazers (12-16) aim to extend a three-game winning run when hosting the Detroit Pistons (22-6) on December 22, 2025 at Moda Center. Monday's game between the Pistons and the Trail Blazers sees the Pistons as 6-point favorites. The game has a point total of 234.5.

Here is everything you need to know to know about the Pistons-Trail Blazers game, from the point spread, moneyline, total Over/Under and expert picks, as well as TV channel and streaming information.

Pistons vs. Trail Blazers Game Information, TV Channel & Odds

• When: Monday, December 22, 2025 at 10 p.m. ET
• Where: Moda Center in Portland, Oregon
• TV: KUNP and FDSDET
• Live Boxscore: FOX Sports

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Pistons vs. Trail Blazers Prediction

ATS Pick: Trail Blazers (+ 6)
O/U Pick: Over (234.5)
Score Prediction: Pistons 119 - Trail Blazers 116

Pistons vs. Trail Blazers Betting Insights

• This year, the Pistons games have gone over 234.5 points scored, their current matchup's total, 10 (out of 28) times.
• A total of 17 Trail Blazers games this season (out of 28) have gone over 234.5 total points scored.
• The Pistons and Trail Blazers average 2.4 more points between them than the total of 234.5 for this game.
• Opponents of the two teams average a combined 1.1 fewer points per game (233.4) than this matchup's total of 234.5 points.
• Detroit has come away with 16 wins in the 21 contests it has been listed as the favorite this season.
• Portland has come away with seven wins in the 17 contests it has been listed as the underdog this season.
• Detroit has a 1-0 record in the last one head-to-head matchups against Portland.
• The Trail Blazers have a 1-0 edge against the spread when taking on the Pistons.

Pistons Recent Trends

• The Pistons are 4-6 against the spread and 7-3 overall over their last 10 games.
• Detroit's average total over the last 10 games is 2.7 points fewer than the 234.5 total given for this matchup.
• The Pistons have 16 wins against the spread in 28 games this season.
• Detroit has an against the spread record of 7-5 in its 12 games when favored by 6 points or more so far this season.
• Pistons games this year have eclipsed the over/under 15 times in 28 opportunities (53.6%).
• The Pistons put up just 2.4 fewer points per game (118.9) than the Trail Blazers give up (121.3).
• Detroit has an 8-4 record against the spread and a 12-0 record overall when scoring more than 121.3 points.
• This season, the Pistons have a 47.9% shooting percentage from the field, which is the same percentage of shots the Trail Blazers' opponents have knocked down.
• In home games, the Pistons sport a better record against the spread (9-6-0) compared to their ATS record in away games (7-6-0).
• Detroit has eclipsed the total in a higher percentage of home games (60%) than road games (46.2%).
• As a moneyline favorite, the Pistons have picked up the win in 10 of 11 games when playing at home, good for a .909 winning percentage. They have won six of 10 games away from home (.600) as a moneyline favorite.

Pistons Recent Stats

Pistons Leaders

• Cade Cunningham posts 27 points, 6.4 rebounds and 9.2 assists per contest. At the other end, he averages 1.4 steals and 0.8 blocks.
• Jalen Duren posts 18 points, 1.7 assists and 11 boards per contest.
• Ausar Thompson averages 11.5 points, 5.7 rebounds and 2.8 assists per game. At the other end, he averages 1.5 steals and 0.8 blocks.
• Isaiah Stewart puts up 10.3 points, 6.2 rebounds and 1.2 assists per contest, shooting 53.3% from the floor and 39.3% from downtown with 1 made 3-pointers per game.
• Duncan Robinson averages 12 points, 2.9 boards and 1.9 assists per game. Defensively he averages 0.9 steals and 0.3 blocks.

Pistons Player Props

Trail Blazers Recent Trends

• The Trail Blazers are 6-4 against the spread and 4-6 overall in their last 10 contests.
• Portland and its opponents have combined to score an average of 236.8 combined points in its last 10 games, 2.3 more than the 234.5 over/under in this matchup.
• The Trail Blazers have 15 wins against the spread in 28 games this year.
• Portland is 5-2 ATS when underdogs by 6 points or more this season.
• The Trail Blazers have hit the over 64.3% of the time this year (18 of 28 games with a set point total).
• The Trail Blazers average 5.9 more points per game (118) than the Pistons allow (112.1).
• Portland has put together a 12-8 ATS record and a 10-10 overall record in games it scores more than 112.1 points.
• The Trail Blazers have shot at a 44.5% rate from the field this season, 0.3 percentage points above the 44.2% shooting opponents of the Pistons have averaged.
• This year, the Trail Blazers are 7-4-0 at home against the spread (.636 winning percentage). On the road, they are 8-9-0 ATS (.471).
• Portland's games have finished above the over/under 72.7% of the time at home (eight of 11), and 58.8% of the time on the road (10 of 17).
• The Trail Blazers' winning percentage at home when moneyline favorites is .333 (1-2), and on the road it is .571 (4-3).

Trail Blazers Recent Stats

Trail Blazers Leaders

• Deni Avdija is averaging 25.8 points, 7.1 rebounds and 6.4 assists per game. He's also sinking 47.1% of his shots from the field and 37% from 3-point range, with 2.4 triples per contest.
• Jerami Grant is putting up 20 points, 4 rebounds and 2.7 assists per contest. He's making 43.6% of his shots from the floor and 38.9% from 3-point range, with 2.5 treys per contest.
• The Trail Blazers are getting 22 points, 4.5 rebounds and 2.5 assists per game from Shaedon Sharpe this season.
• The Trail Blazers are getting 12.6 points, 5.3 rebounds and 2.9 assists per game from Toumani Camara this year.
• The Trail Blazers are getting 10.3 points, 10.3 rebounds and 1.8 assists per game from Donovan Clingan this season.

Trail Blazers Player Props

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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