Cavaliers vs. Clippers Prediction, Odds, Picks - Nov. 23

The Los Angeles Clippers (5-11) will turn to James Harden (ninth in NBA, 28.4 points per game) to help overcome Donovan Mitchell (sixth in league, 30.3) and the Cleveland Cavaliers (11-6) on November 23, 2025 at Rocket Arena. The Cavaliers are currently healthy 8-point favorites over the Clippers. A 229.5-point over/under has been set for the game.

Check out everything you need to know to know about the Cavaliers-Clippers game, from the point spread, moneyline, total Over/Under and expert picks, as well as TV channel and streaming information.

Cavaliers vs. Clippers Game Information, TV Channel & Odds

• When: Sunday, November 23, 2025 at 6 p.m. ET
• Where: Rocket Arena in Cleveland, Ohio
• TV: FDSOH and FDSSC
• Live Boxscore: FOX Sports

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Cavaliers vs. Clippers Prediction

ATS Pick: Cavaliers (- 8)
O/U Pick: Over (229.5)
Score Prediction: Cavaliers 122 - Clippers 111

Cavaliers vs. Clippers Betting Insights

• Cavaliers games have gone over 229.5 points scored, their current matchup's total, 10 times (out of 17) this year.
• A total of 10 Clippers games this season (out of 16) have gone over 229.5 total points scored.
• The Cavaliers and Clippers average 2.7 more points between them than the total of 229.5 for this matchup.
• Opponents of the two teams average a combined 3.2 more points per game (232.7) than this game's over/under of 229.5 points.
• Cleveland has been chosen as the favorite in 15 games this year and has walked away with the win 10 times (66.7%) in those games.
• Los Angeles has been posted as the underdog six times this season but has yet walk away from any of those games with an upset.
• Cleveland and Los Angeles have each won one of their last two head-to-head matchups.
• The Clippers hold a 2-0 advantage against the spread when taking on the Cavaliers.

Cavaliers Recent Trends

• The Cavaliers have gone 7-3 over their past 10 games, with a 4-6 record against the spread in that span.
• Cleveland and its opponents have combined to score an average of 239.2 points in its last 10 games, 9.7 more than the 229.5 over/under in this matchup.
• In the Cavaliers' 17 games this season, they have six wins against the spread.
• This season, Cleveland has just two ATS wins in six games as a favorite of 8 points or more.
• Cavaliers games this year have hit the over eight times in 16 opportunities (50%).
• The Cavaliers score only 2.8 more points per game (119.9) than the Clippers give up (117.1).
• When Cleveland puts up more than 117.1 points, it is 4-5 against the spread and 8-1 overall.
• The Cavaliers are shooting 46.0% from the field this season, 1.1 percentage points lower than the 47.1% the Clippers allow to opponents.
• The Cavaliers have done a better job covering the spread in road games (3-4-0) than they have at home (3-7-0).
• Cleveland has gone over the total in a lower percentage of home games (30%) than games on the road (71.4%).
• The Cavaliers have won a higher percentage of their games as a moneyline favorite when playing at home, going 7-2 (.778). On the road as a moneyline favorite, they have a record of 3-3 (.500).

Cavaliers Recent Stats

Cavaliers Leaders

• Mitchell averages 30.3 points, 4.8 rebounds and 5.3 assists per contest. Defensively, he averages 1.5 steals and 0.4 blocks.
• Evan Mobley averages 19.0 points, 8.8 rebounds and 4.0 assists per contest. Defensively, he averages 1.1 steals and 1.6 blocks (eighth in NBA).
• De'Andre Hunter averages 18.1 points, 4.9 rebounds and 2.7 assists per game. At the other end, he averages 0.7 steals and 0.2 blocks.
• Jaylon Tyson posts 11.3 points, 4.3 boards and 1.9 assists per game, shooting 51.5% from the field and 47.3% from beyond the arc (sixth in league) with 2.2 made 3-pointers per contest.
• Dean Wade averages 5.3 points, 3.9 boards and 1.5 assists per contest, shooting 37.7% from the floor and 30.4% from beyond the arc with 1.1 made 3-pointers per game.

Cavaliers Player Props

Clippers Recent Trends

• The Clippers have a 4-6 record against the spread while going 2-8 overall over their past 10 games.
• Los Angeles' average total over the last 10 games is 7.4 points fewer than the 229.5 over/under listed for this matchup.
• The Clippers are 5-11-0 against the spread this season.
• Los Angeles has yet to cover the spread this year when underdogs by 8 points or more.
• Clippers games this year have eclipsed the over/under 10 times in 16 opportunities (62.5%).
• The Clippers average just 3.3 fewer points per game (112.3) than the Cavaliers give up (115.6).
• Los Angeles has put together a 4-3 ATS record and a 4-3 overall record in games it scores more than 115.6 points.
• The Clippers are shooting 47.1% from the field, 1.2% higher than the 45.9% the Cavaliers' opponents have shot this season.
• The Clippers have been better against the spread on the road (4-4-0) than at home (1-7-0) this season.
• Los Angeles' games have finished above the over/under 62.5% of the time both at home (five of eight) and on the road (five of eight) this year.
• The Clippers' winning percentage when moneyline favorites, both at home (3-3 record) and on the road (2-2), is .500.

Clippers Recent Stats

Clippers Leaders

• Harden is putting up 28.4 points, 6.0 rebounds and 8.5 assists per contest. He's also draining 46.1% of his shots from the floor and 40.8% from 3-point range, with 4.1 triples per game (second in league).
• On a per-game basis, Ivica Zubac gives the Clippers 16.0 points, 11.2 rebounds and 2.3 assists. He also averages 0.5 steals and 0.9 blocked shots.
• The Clippers are getting 11.6 points, 4.9 rebounds and 0.6 assists per game from John Collins this season.
• Kris Dunn is averaging 6.9 points, 2.5 rebounds and 2.7 assists per game. He is sinking 47.8% of his shots from the floor.
• The Clippers are getting 24.3 points, 5.7 rebounds and 3.5 assists per game from Kawhi Leonard this year.

Clippers Player Props

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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