Yankees vs. Orioles Prediction, Odds, Picks - June 21

Aaron Judge and Ryan O'Hearn are the hottest hitters on the New York Yankees and Baltimore Orioles, who play on Saturday at Yankee Stadium, at 1:05 p.m. ET. Bookmakers list the Yankees as -177 favorites on the moneyline, while giving the underdog Orioles +148 moneyline odds. New York is favored on the run line (-1.5 with +114 odds). The total for the matchup has been set at 9.5 runs.

Here is everything you need from a betting perspective on the Yankees-Orioles game, regarding the run line, moneyline and total, plus expert picks.

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Orioles vs. Yankees Highlights | MLB on FOX

Check out the best highlights between the Baltimore Orioles and New York Yankees.

Yankees vs. Orioles Game Information & Odds

• When: Saturday, June 21, 2025 at 1:05 p.m. ET
• Where: Yankee Stadium in The Bronx, New York
• How to watch on TV: YES and MASN

Yankees vs. Orioles Prediction

• Score Prediction: Yankees 4, Orioles 3
• Total Prediction: Under 9.5 runs
• Win Probabilities: Yankees 60%, Orioles 40%

Yankees vs. Orioles Betting Insights

• The Yankees have been favorites in 66 games this season and won 40 (60.6%) of those contests.
• New York is 14-9 this season when entering a game favored by -177 or more on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that the Yankees have a 63.9% chance to win.
• The Orioles have been underdogs in 32 games this season and have come away with the win 14 times (43.8%) in those contests.
• This season, Baltimore has been victorious one time in three chances when named as an underdog of at least +148 or longer on the moneyline.
• The moneyline set for this matchup implies the Orioles have a 40.3% chance of coming away with a victory in the contest.

Yankees Recent Betting Performance

• The Yankees were the moneyline favorite for nine of their last 10 games, and they went 3-6 in those matchups.
• Over their last 10 outings, the Yankees and their opponents combined to go over the run total one time (all 10 of the games had set totals).
• The Yankees' ATS record is 3-7-0 over their past 10 games.

Yankees Recent Stats

Yankees Player Insights

• Judge's 27 round-trippers and 61 RBI both lead the Yankees, on top of his team-high .371 average.
• Judge's home runs rank him second in the majors, and he is fourth in RBI.
• Judge carries a two-game hitting streak into this matchup. During his last five outings he is batting .278 with a double, a home run, four walks and an RBI.
• Cody Bellinger is batting .259 with 12 doubles, three triples, 10 home runs and 27 walks.
• Bellinger ranks 65th in home runs in MLB, and 56th in RBI.
• Bellinger has three straight games with at least one hit. During his last five outings he is hitting .350 with a double, a home run, a walk and two RBIs.
• Paul Goldschmidt has 15 doubles, a triple, eight home runs and 24 walks while batting .298.
• Trent Grisham is batting .241 with five doubles, a triple, 14 home runs and 33 walks.

Yankees Team Props

Orioles Recent Betting Performance

• In five games as underdogs over the last 10 matchups, the Orioles have a record of 2-3.
• In their last 10 games with a total, the Orioles and their opponents have combined to hit the over four times.
• The Orioles have a record of 6-4-0 ATS over their last 10 games.

Orioles Recent Stats

Orioles Player Insights

• O'Hearn leads the Orioles with a team-leading batting average of .304.
• In all of the majors, O'Hearn is 65th in home runs and 120th in RBI.
• Gunnar Henderson has 14 doubles, two triples, eight home runs and 24 walks while batting .285.
• Henderson is currently 110th in homers and 178th in RBI in the major leagues.
• Cedric Mullins has been a significant run producer for the Orioles with 12 home runs and 35 runs batted in.
• Adley Rutschman is batting .227 with nine doubles, a triple, eight home runs and 32 walks.

Orioles Team Props

Orioles vs. Yankees Highlights | MLB on FOX

Check out the best highlights between the Baltimore Orioles and New York Yankees.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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