Twins vs. Padres Prediction, Odds, Picks - August 31

The Minnesota Twins and Byron Buxton will square off against the San Diego Padres and Fernando Tatis Jr. on Sunday at 1:05 p.m. ET, in the final game of a three-game series at Target Field. Oddsmakers list the Twins as -122 favorites on the moneyline, while giving the underdog Padres +102 moneyline odds to win. Minnesota is favored on the run line (-1.5). The over/under is 8.5 runs for the contest (with -117 odds on the over and -104 odds to go under).

Here's everything you need from a betting perspective on the Twins-Padres game, regarding the run line, moneyline and total, plus expert picks.

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Padres vs. Twins Highlights | MLB on FOX

Check out the best moments between the San Diego Padres and Minnesota Twins.

Twins vs. Padres Game Information & Odds

• When: Sunday, August 31, 2025 at 1:05 p.m. ET
• Where: Target Field in Minneapolis, Minnesota
• How to watch on TV: Roku

Twins vs. Padres Prediction

• Score Prediction: Padres 5, Twins 4
• Total Prediction: Under 8.5 runs
• Win Probabilities: Twins 51%, Padres 49%

Twins vs. Padres Betting Insights

• The Twins have won 37, or 48.7%, of the 76 games they've played as favorites this season.
• Minnesota has a record of 29-22, a 56.9% win rate, when favored by -122 or more by bookmakers this season.
• The moneyline for this contest implies a 55% chance of a victory for the Twins.
• The Padres have won in 32, or 50.8%, of the 63 contests they have been named as odds-on underdogs this year.
• This year, San Diego has won 25 of 53 games when listed as at least +102 or worse on the moneyline.
• The moneyline set for this matchup implies the Padres have a 49.5% chance of walking away with the win.

Twins Recent Betting Performance

• The Twins played as the moneyline favorite for four of their last 10 games, and they finished 1-3 in those matchups.
• Over their last 10 matchups, the Twins and their opponents combined to go over the run total eight times (all 10 games had set totals).
• The Twins have put together a 4-6-0 record against the spread over their past 10 games.

Twins Recent Stats

Twins Player Insights

• Buxton's 28 home runs and 68 RBI both lead the Twins, on top of his team-high .270 average.
• Buxton is 13th in home runs and 55th in RBI among all hitters in the majors.
• Buxton has collected a hit in three straight games. During his last five outings he is batting .278 with three home runs, two walks and six RBIs.
• Trevor Larnach is hitting .249 with 19 doubles, a triple, 16 home runs and 45 walks.
• Larnach ranks 94th in home runs and 107th in RBI in the bigs.
• Larnach has two games in a row with at least one hit. During his last five outings he is batting .438 with a double, two walks and three RBIs.
• Brooks Lee has 13 doubles, a triple, 14 home runs and 25 walks while hitting .244.
• Ryan Jeffers has 24 doubles, nine home runs and 44 walks while batting .259.

Twins Team Props

Padres Recent Betting Performance

• The Padres have played as underdogs in five of their past 10 games and won three of those contests.
• When it comes to hitting the over, the Padres and their opponents are 7-3-0 in their last 10 games with a total.
• The Padres are 6-4-0 ATS over their last 10 games.

Padres Recent Stats

Padres Player Insights

• Tatis is batting .266 with 27 doubles, two triples, 18 home runs and 81 walks.
• In all of the big leagues, Tatis is 74th in home runs and 98th in RBI.
• Tatis takes a hitting streak of five games into this game. During his last five outings he is batting .304 with two doubles, a home run, two walks and five RBIs.
• Manny Machado has a club-best 79 runs batted in and .287 batting average.
• Machado ranks 53rd overall in homers and 23rd in RBI this season.
• Luis Arraez is batting .283 with 29 doubles, four triples, six home runs and 27 walks.
• Ramon Laureano leads the Padres with 22 home runs.

Padres Team Props

Padres vs. Twins Highlights | MLB on FOX

Check out the best moments between the San Diego Padres and Minnesota Twins.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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