Reds vs. Pirates Prediction, Odds, Picks - May 20

TJ Friedl and the Cincinnati Reds hit the field on Tuesday at PNC Park against Bailey Falter, who is starting for the Pittsburgh Pirates. First pitch is at 6:40 p.m. ET for the second game of a three-game series. The Reds are listed as -146 moneyline favorites in this matchup with the Pirates (+122). Cincinnati (-1.5) is the favorite on the run line. The total is 8 runs for the matchup.

Take a look at everything you need from a betting perspective on the Reds-Pirates game, regarding the run line, moneyline and total, plus expert picks.

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Reds vs. Pirates Highlights | MLB on FOX

Check out the top moments from this MLB game between Cincinnati Reds and the Pittsburgh Pirates!

Reds vs. Pirates Game Information & Odds

• When: Tuesday, May 20, 2025 at 6:40 p.m. ET
• Where: PNC Park in Pittsburgh, Pennsylvania
• How to watch on TV: SportsNet PT and FDSOH

Reds vs. Pirates Prediction

• Score Prediction: Reds 5, Pirates 4
• Total Prediction: Over 8 runs
• Win Probabilities: Reds 52%, Pirates 48%

Reds vs. Pirates Betting Insights

• The Reds have won 13, or 54.2%, of the 24 games they've played as favorites this season.
• Cincinnati has entered 10 games this season favored by -146 or more and is 6-4 in those contests.
• The implied probability of a win from the Reds, based on the moneyline, is 59.3%.
• The Pirates have been underdogs in 32 games this season and have come away with the win 10 times (31.2%) in those contests.
• This season, Pittsburgh has been victorious seven times in 23 chances when named as an underdog of at least +122 or worse on the moneyline.
• The moneyline set for this matchup implies the Pirates have a 45% chance of coming away with a victory in the contest.

Reds Recent Betting Performance

• The Reds played as the moneyline favorite in five of their last 10 games, and finished 3-2 in those matchups.
• In their last 10 matchups, the Reds and their opponents combined to hit the over on the run total one time (all 10 games had set totals).
• The Reds have put together a 6-4-0 record against the spread over their past 10 games.

Reds Recent Stats

Reds Player Insights

• Elly De La Cruz paces the Reds in home runs (eight) and runs batted in (33).
• Including all MLB hitters, De La Cruz is 90th in batting average, 90th in on-base percentage, and 82nd in slugging.
• Friedl has eight doubles, a triple, three home runs and 23 walks while hitting .275.
• Friedl ranks 175th in homers and 121st in RBI among all major league batters this season.
• Gavin Lux paces the Reds with a .294 batting average.
• Austin Hays is batting .330 with six doubles, six home runs and seven walks.
• Hays has recorded at least one hit in six straight games. In his last 10 outings he is batting .278 with three doubles, a home run, a walk and six RBIs.

Reds Team Props

Pirates Recent Betting Performance

• The Pirates have played as underdogs in nine of their past 10 games and won three of those contests.
• When it comes to hitting the over, the Pirates and their opponents are 1-7-2 in their last 10 games with a total.
• The Pirates have six wins against the spread in their last 10 chances.

Pirates Recent Stats

Pirates Player Insights

• Oneil Cruz has hit a team-best eight home runs.
• In all of the majors, Cruz is 40th in homers and 121st in RBI.
• Andrew McCutchen is batting .241 with seven doubles, three home runs and 20 walks.
• McCutchen ranks 175th in homers and 179th in RBI among all hitters in the big leagues.
• Bryan Reynolds paces the Pirates with 22 runs batted in.
• Isiah Kiner-Falefa is batting .282 with three doubles, a triple, a home run and eight walks.

Pirates Team Props

Reds vs. Pirates Highlights | MLB on FOX

Check out the top moments from this MLB game between Cincinnati Reds and the Pittsburgh Pirates!

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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