Reds vs. Nationals Prediction, Odds, Picks - May 2

Mitchell Parker takes the mound for the Washington Nationals on Friday at Great American Ball Park against Spencer Steer and the Cincinnati Reds. First pitch is at 6:10 p.m. ET. The Reds have been listed as -202 moneyline favorites for this matchup with the Nationals (+168). Cincinnati is favored on the run line (-1.5). The over/under is 8.5 runs for the game (with -120 odds on the over and +100 odds to go under).

Take a look at everything you need from a betting perspective on the Reds-Nationals game, regarding the run line, moneyline and total, plus expert picks.

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Reds vs. Nationals Game Information & Odds

• When: Friday, May 2, 2025 at 6:10 p.m. ET
• Where: Great American Ball Park in Cincinnati, Ohio
• How to watch on TV: FDSOH and MASN2

Reds vs. Nationals Prediction

• Score Prediction: Reds 5, Nationals 3
• Total Prediction: Under 8.5 runs
• Win Probabilities: Reds 58%, Nationals 42%

Reds vs. Nationals Betting Insights

• The Reds have entered the game as favorites 16 times this season and won nine, or 56.2%, of those games.
• Cincinnati has played as favorites of -202 or more once this season and won that game.
• The implied probability of a win from the Reds, based on the moneyline, is 66.9%.
• The Nationals have been victorious in 12, or 46.2%, of the 26 contests they have been chosen as underdogs in this season.
• Washington has been listed as an underdog of +168 or more on two occasions this season and lost both games.
• The Nationals have an implied victory probability of 37.3% according to the moneyline set for this matchup.

Reds Recent Betting Performance

• The Reds have a 5-4 record over the nine games they were favored on the moneyline in their last 10 matchups.
• In their last 10 matchups, the Reds and their opponents combined to go over the run total four times (all 10 of the games had set totals).
• The Reds are 5-5-0 against the spread over their past 10 games.

Reds Recent Stats

Reds Player Insights

• Elly De La Cruz has gone yard five times in the 2025 campaign while driving in 24 runs, both totals that lead the Reds.
• Including all MLB hitters, De La Cruz is 53rd in batting average, 57th in on-base percentage, and 66th in slugging.
• TJ Friedl is hitting .274 with six doubles, a triple, a home run and 11 walks.
• Including all major league hitters, Friedl is 219th in homers and 128th in RBI.
• Gavin Lux leads the Reds with a .317 batting average.
• Noelvi Marte has four doubles, a triple, three home runs and five walks while batting .328.

Reds Team Props

Nationals Recent Betting Performance

• The Nationals have played as underdogs in nine of their past 10 games and won five of those contests.
• When it comes to hitting the over, the Nationals and their opponents are 4-6-0 in their last 10 games with a total.
• The Nationals have won seven of their last 10 games against the spread.

Nationals Recent Stats

Nationals Player Insights

• James Wood leads the Nationals with nine home runs.
• In all of MLB, Wood ranks fourth in home runs and 19th in RBI.
• Nathaniel Lowe has put up 25 runs batted in to pace his team.
• Lowe is 31st in homers and ninth in RBI among all major league hitters this season.
• Luis Garcia is hitting .253 with five doubles, two home runs and eight walks.
• Keibert Ruiz leads the team in batting average with a mark of .299.

Nationals Team Props

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Check out the best moments between the Washington Nationals and the Philadelphia Phillies.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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