Red Sox vs. Tigers Prediction, Odds, Picks - September 26

Trevor Story and the Boston Red Sox square off against Jahmai Jones and the Detroit Tigers at Fenway Park on Friday, at 7:10 p.m. ET. The favored Red Sox have -122 moneyline odds to win against the underdog Tigers, who are listed at +102. Detroit is a 1.5-run favorite (at +163 odds). The matchup's total has been set at 9 runs.

Here's everything you need to know from a betting perspective on the Red Sox-Tigers game, regarding the run line, moneyline and total, plus expert picks.

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Red Sox vs. Tigers Game Information & Odds

• When: Friday, September 26, 2025 at 7:10 p.m. ET
• Where: Fenway Park in Boston, Massachusetts
• How to watch on TV: Apple TV+

Red Sox vs. Tigers Prediction

• Score Prediction: Red Sox 4, Tigers 3
• Total Prediction: Under 9 runs
• Win Probabilities: Red Sox 56%, Tigers 44%

Red Sox vs. Tigers Betting Insights

• This season, the Red Sox have won 57 out of the 98 games, or 58.2%, in which they've been favored.
• Boston has entered 72 games this season favored by -122 or more and is 42-30 in those contests.
• The implied probability of a win from the Red Sox, based on the moneyline, is 55%.
• The Tigers have come away with 23 wins in the 48 contests they have been listed as the underdogs in this season.
• This season, Detroit has been victorious 10 times in 26 chances when named as an underdog of at least +102 or longer on the moneyline.
• The Tigers have an implied victory probability of 49.5% according to the moneyline set by sportsbooks for this matchup.

Red Sox Recent Betting Performance

• The Red Sox have a 4-3 record from the seven games they were moneyline favorites over their last 10 matchups.
• Over their last 10 outings, the Red Sox and their opponents combined to go over the run total five times (all 10 games had set totals).
• The Red Sox's ATS record is 5-5-0 over their past 10 games.

Red Sox Recent Stats

Red Sox Player Insights

• Jarren Duran is batting .257 with 40 doubles, 13 triples, 16 home runs and 60 walks.
• Duran ranks 123rd in homers and 48th in RBI among all hitters in baseball.
• Story has put his power on display as he leads his team with 25 home runs and 96 runs batted in.
• Story is 46th in homers in baseball, and 19th in RBI.
• Story heads into this matchup looking for his sixth game in a row with a hit. In his last five games he is hitting .304 with a double, a walk and two RBIs.
• Alex Bregman leads the Red Sox with a .273 batting average.
• Ceddanne Rafaela is hitting .245 with 32 doubles, three triples, 16 home runs and 27 walks.

Red Sox Team Props

Tigers Recent Betting Performance

• Over the past 10 games, the Tigers have been underdogs twice and split those games 1-1.
• In their last 10 games with a total, the Tigers and their opponents have failed to hit the over six times.
• The Tigers are 2-8-0 ATS over their last 10 games.

Tigers Recent Stats

Tigers Player Insights

• Gleyber Torres is batting .258 with 22 doubles, 16 home runs and 85 walks.
• Among all hitters in the big leagues, Torres ranks 123rd in home runs and 68th in RBI.
• Riley Greene proven to be a run producer as he leads his team with 36 home runs and 111 RBI, with a team-leading .262 batting average.
• Greene is currently 10th in homers and fifth in RBI in the big leagues.
• Spencer Torkelson is batting .240 with 27 doubles, a triple, 31 home runs and 71 walks.
• Zach McKinstry is batting .261 with 23 doubles, 11 triples, 12 home runs and 46 walks.

Tigers Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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