Red Sox vs. Cubs Prediction, Odds, Picks - July 20

Garrett Crochet and Cade Horton are the projected starters when the Boston Red Sox and Chicago Cubs square off on Sunday at Wrigley Field. The Red Sox are -136 moneyline favorites for this matchup with the Cubs (+115). Boston is a 1.5-run favorite (at +134 odds). The total is 6.5 runs for the game.

Check out everything you need to know from a betting perspective on the Red Sox-Cubs game, regarding the run line, moneyline and total, plus expert picks.

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Cubs vs. Red Sox Highlights | MLB on FOX

Check out the best moments from this MLB matchup between the Chicago Cubs and the Boston Red Sox.

Red Sox vs. Cubs Game Information & Odds

• When: Sunday, July 20, 2025 at 2:20 p.m. ET
• Where: Wrigley Field in Chicago, Illinois
• How to watch on TV: NESN

Red Sox vs. Cubs Prediction

• Score Prediction: Cubs 5, Red Sox 4
• Total Prediction: Over 6.5 runs
• Win Probabilities: Red Sox 56%, Cubs 44%

Red Sox vs. Cubs Betting Insights

• This season, the Red Sox have won 36 out of the 62 games, or 58.1%, in which they've been favored.
• Boston has a record of 14-13, a 51.9% win rate, when favored by -136 or more by sportsbooks this season.
• The implied probability of a win from the Red Sox, based on the moneyline, is 57.6%.
• The Cubs have been underdogs in 31 games this season and have come away with the win 12 times (38.7%) in those contests.
• Chicago has a win-loss record of 4-8 when favored by +115 or worse by oddsmakers this year.
• The moneyline set for this matchup implies the Cubs have a 46.5% chance of coming away with a victory in the contest.

Red Sox Recent Betting Performance

• The Red Sox won all of the eight games it played while the moneyline favorite in their last 10 matchups.
• Over their last 10 outings (all 10 of them had set totals), the Red Sox and their opponents combined to go over the run total four times.
• The Red Sox have put together a 7-3-0 record against the spread over their past 10 games.

Red Sox Recent Stats

Red Sox Player Insights

• Ceddanne Rafaela has a team-best batting average of .271.
• Rafaela is 61st in homers and 66th in RBI among all hitters in baseball.
• Rafaela carries a 12-game hitting streak into this matchup. During his last 10 games he is batting .405 with three doubles, five home runs, a walk and 14 RBIs.
• Jarren Duran is hitting .259 with 25 doubles, 10 triples, eight home runs and 32 walks.
• Duran is 154th in homers and 55th in RBI among all batters in MLB.
• Wilyer Abreu paces the Red Sox with 18 home runs.
• Trevor Story's 58 runs batted in lead his team.

Red Sox Team Props

Cubs Recent Betting Performance

• The Cubs have played as underdogs in four of their past 10 games and won two of those contests.
• When it comes to hitting the over, the Cubs and their opponents are 3-7-0 in their last 10 games with a total.
• The Cubs are 6-4-0 ATS over their last 10 games.

Cubs Recent Stats

Cubs Player Insights

• Kyle Tucker is batting .281 with 19 doubles, four triples, 18 home runs and 61 walks.
• Tucker's home run total puts him 27th in the majors, and he ranks 28th in RBI.
• Pete Crow-Armstrong's 26 home runs lead his team.
• Crow-Armstrong is sixth in home runs and eighth in RBI among all MLB hitters this year.
• Seiya Suzuki has been solid source of run production for the Cubs with 26 long balls and 80 runs batted in.
• Michael Busch leads the Cubs with a team-high batting average of .289.

Cubs Team Props

Cubs vs. Red Sox Highlights | MLB on FOX

Check out the best moments from this MLB matchup between the Chicago Cubs and the Boston Red Sox.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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