Rays vs. White Sox Prediction, Odds, Picks - July 21

Shane Baz and Sean Burke will start for their respective teams when the Tampa Bay Rays and the Chicago White Sox play on Monday at George M. Steinbrenner Field, at 7:35 p.m. ET. The Rays are the favorite in this one, at -220, while the underdog White Sox have +180 odds to upset. Tampa Bay is a 1.5-run favorite (at -110 odds). A 9-run total is set in this matchup.

Check out everything you need to know from a betting perspective on the Rays-White Sox game, regarding the run line, moneyline and total, plus expert picks.

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Orioles vs. Rays Highlights | MLB on FOX

Check out the best moments between the Baltimore Orioles and the Tampa Bay Rays.

Rays vs. White Sox Game Information & Odds

• When: Monday, July 21, 2025 at 7:35 p.m. ET
• Where: George M. Steinbrenner Field in Tampa, Florida
• How to watch on TV: FDSSUN and CHSN

Rays vs. White Sox Prediction

• Score Prediction: Rays 5, White Sox 3
• Total Prediction: Under 9 runs
• Win Probabilities: Rays 58%, White Sox 42%

Rays vs. White Sox Betting Insights

• The Rays have entered the game as favorites 53 times this season and won 31, or 58.5%, of those games.
• Tampa Bay has played as favorites of -220 or more once this season and won that game.
• Oddsmakers have implied with the moneyline set for this matchup that the Rays have a 68.8% chance to win.
• The White Sox have been chosen as underdogs in 98 games this year and have walked away with the win 34 times (34.7%) in those games.
• Chicago has a mark of 5-28 in contests where oddsmakers favor it by +180 or worse on the moneyline.
• The White Sox have an implied victory probability of 35.7% according to the moneyline set by sportsbooks for this matchup.

Rays Recent Betting Performance

• The Rays were the moneyline favorite in four of their last 10 games, and they finished 2-2 in those matchups.
• In their last 10 matchups -- all had a set run total -- the Rays and their opponents combined to go over the total two times.
• The Rays' record against the spread is 3-7-0 over their past 10 games.

Rays Recent Stats

Rays Player Insights

• Yandy Diaz is batting .294 with 19 doubles, a triple, 15 home runs and 33 walks.
• Among all hitters in MLB, Diaz's home run total ranks him 52nd, and his RBI tally puts him 28th.
• Diaz has collected a hit in five straight games. In his last five games he is hitting .500 with a double, a home run, four walks and four RBIs.
• Junior Caminero's 25 home runs and 65 runs batted in both lead his team.
• Among all MLB hitters, Caminero ranks eighth in home runs and 13th in RBI.
• Caminero enters this game looking for his fifth game in a row with a hit. During his last five outings he is hitting .333 with a double, two home runs and five RBIs.
• Jonathan Aranda leads the Rays with a team-best batting average of .316.
• Brandon Lowe is batting .269 with 11 doubles, 19 home runs and 24 walks.

Rays Team Props

White Sox Recent Betting Performance

• In 10 games over the last 10 matchups when set as underdogs by bookmakers, the White Sox had a record of 5-5.
• In their last 10 games with a total, the White Sox and their opponents are 5-5-0 when it comes to hitting the over.
• The White Sox have six wins against the spread in their last 10 chances.

White Sox Recent Stats

White Sox Player Insights

• Miguel Vargas paces the White Sox with 11 home runs and runs batted in, driving in 38.
• Among all hitters in the majors, Vargas is 108th in home runs and 118th in RBI.
• Andrew Benintendi's 11 home runs are a team-high total.
• Benintendi is currently 108th in homers and 127th in RBI in the major leagues.
• Luis Robert leads the White Sox with 38 runs batted in.
• Lenyn Sosa paces the White Sox with a .270 batting average.

White Sox Team Props

Orioles vs. Rays Highlights | MLB on FOX

Check out the best moments between the Baltimore Orioles and the Tampa Bay Rays.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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