Rays vs. Red Sox Prediction, Odds, Picks - April 16

Sean Newcomb gets the nod on the mound for the Boston Red Sox looking to slow down Jonathan Aranda and the Tampa Bay Rays on Wednesday at 7:05 p.m. ET. The Rays are -132 moneyline favorites for this matchup against the Red Sox (+111). Tampa Bay is the run-line favorite (-1.5). The matchup's total has been set at 9 runs.

Check out everything you need to know from a betting perspective on the Rays-Red Sox game, regarding the run line, moneyline and total, plus expert picks.

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Red Sox vs. Rays Highlights | MLB on FOX

Check out the top moments from this game between the Boston Red Sox and the Tampa Bay Rays!

Rays vs. Red Sox Game Information & Odds

• When: Wednesday, April 16, 2025 at 7:05 p.m. ET
• Where: George M. Steinbrenner Field in Tampa, Florida
• How to watch on TV: FDSSUN and NESN

Rays vs. Red Sox Prediction

• Score Prediction: Rays 6, Red Sox 5
• Total Prediction: Over 9 runs
• Win Probabilities: Rays 54%, Red Sox 46%

Rays vs. Red Sox Betting Insights

• This season, the Rays have been favored 13 times and won seven, or 53.8%, of those games.
• Tampa Bay has entered nine games this season favored by -132 or more and is 6-3 in those contests.
• Oddsmakers have implied with the moneyline set for this matchup that the Rays have a 56.9% chance to win.
• The Red Sox have been victorious in two of the six contests they have been chosen as underdogs in this season.
• Boston has been listed as an underdog of +111 or more on two occasions this season and lost both games.
• Sportsbooks have implied with the moneyline set for this matchup that the Red Sox have a 47.4% chance of pulling out a win.

Rays Recent Betting Performance

• The Rays played as the moneyline favorite in eight of their last 10 games, and they went 3-5 in those matchups.
• Over their last 10 outings (all had set totals), the Rays combined with their opponents to go over the total seven times.
• The Rays have a 3-7-0 record against the spread over their past 10 games.

Rays Recent Stats

Rays Player Insights

• Aranda comes into Wednesday's game as the Rays top run producer, accumulating 11 RBI while crushing three round-trippers in 2025. His .413 average is also best on the squad.
• Including all MLB hitters, Aranda ranks first in batting average, second in on-base percentage, and first in slugging.
• Aranda has collected a hit in four straight games. During his last five outings he is batting .500 with a double, two home runs, three walks and seven RBI.
• Kameron Misner is batting .395 with four doubles, a triple, three home runs and three walks.
• Misner carries a four-game streak with at least one hit into this contest. During his last five outings he is hitting .412 with a double, two home runs, two walks and four RBI.
• Junior Caminero paces the Rays with four home runs.
• Yandy Diaz has three doubles, three home runs and three walks while batting .225.
• Diaz has recorded at least one hit in five games in a row. During his last five outings he is batting .364 with a double, two home runs, a walk and four RBI.

Rays Team Props

Red Sox Recent Betting Performance

• The Red Sox have been underdogs twice in the last 10 games and split those matchups 1-1.
• In their last 10 games with a total, the Red Sox and their opponents have failed to hit the over six times.
• The Red Sox have a record of 3-7-0 ATS over their last 10 games.

Red Sox Recent Stats

Red Sox Player Insights

• Wilyer Abreu is hitting .310 with four doubles, three home runs and 13 walks.
• Among all hitters in the majors, Abreu's home run total ranks 50th and his RBI tally ranks 21st.
• Kristian Campbell is batting .302 with four doubles, three home runs and 10 walks.
• Campbell is 50th in home runs and 139th in RBI among all hitters in the big leagues.
• Jarren Duran is hitting .234 with three doubles, a triple, a home run and seven walks.
• Trevor Story is batting .311 with two doubles, three home runs and two walks.

Red Sox Team Props

Red Sox vs. Rays Highlights | MLB on FOX

Check out the top moments from this game between the Boston Red Sox and the Tampa Bay Rays!

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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