Rays vs. Cubs Prediction, Odds, Picks - September 13

Junior Caminero and the Tampa Bay Rays will try to outdo Ian Happ and the Chicago Cubs at Wrigley Field on Saturday at 2:20 p.m. ET. The Rays are the favorite in this one, at -112, while the underdog Cubs have -107 odds to win. Tampa Bay is favored on the run line (-1.5). An 8-run total is set for the contest.

Here is everything you need from a betting perspective on the Rays-Cubs game, regarding the run line, moneyline and total, plus expert picks.

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Rays vs. Cubs Game Information & Odds

• When: Saturday, September 13, 2025 at 2:20 p.m. ET
• Where: Wrigley Field in Chicago, Illinois
• How to watch on TV: MARQ and FDSSUN

Rays vs. Cubs Prediction

• Score Prediction: Cubs 5, Rays 4
• Total Prediction: Over 8 runs
• Win Probabilities: Rays 54%, Cubs 46%

Rays vs. Cubs Betting Insights

• The Rays have won 43, or 57.3%, of the 75 games they've played as favorites this season.
• Tampa Bay has a record of 41-29, a 58.6% win rate, when favored by -112 or more by bookmakers this season.
• The oddsmakers' moneyline implies a 52.8% chance of a victory for the Rays.
• The Cubs have won in 17, or 42.5%, of the 40 contests they have been named as odds-on underdogs this year.
• This season, Chicago has been victorious 17 times in 38 chances when named as an underdog of at least -107 or worse on the moneyline.
• Oddsmakers have implied with the moneyline set for this matchup that the Cubs have a 51.7% chance of pulling out a win.

Rays Recent Betting Performance

• The Rays went 2-5 over the seven games they were favored on the moneyline in their last 10 matchups.
• Over their last 10 matchups (all 10 of them had set totals), the Rays and their opponents combined to go over the run total six times.
• The Rays' ATS record is 3-7-0 over their past 10 games.

Rays Recent Stats

Rays Player Insights

• Caminero has gone yard 42 times in the 2025 campaign while driving in 106 runs, both totals that lead the Rays.
• In all of the majors, Caminero is sixth in homers and sixth in RBI.
• Yandy Diaz's .290 batting average leads his team.
• Diaz is 50th in home runs and 40th in RBI among all hitters in MLB.
• Brandon Lowe has 17 doubles, 28 home runs and 36 walks while hitting .260.
• Chandler Simpson has 11 doubles, three triples and 18 walks while hitting .291.
• Simpson is riding a two-game hitting streak into this one. In his last five games he is hitting .350 with an RBI.

Rays Team Props

Cubs Recent Betting Performance

• Over the past 10 games, the Cubs have been underdogs just once and won that contest.
• In their last 10 games with a total, the Cubs and their opponents have combined to hit the over four times.
• The Cubs have four wins against the spread in their last 10 chances.

Cubs Recent Stats

Cubs Player Insights

• Nico Hoerner leads the Cubs with a team-leading batting average of .296.
• Among all hitters in MLB, Hoerner's home run total is 269th and his RBI tally is 119th.
• Hoerner has collected a hit in seven straight games. During his last 10 outings he is hitting .375 with four doubles, a triple, a home run, four walks and two RBIs.
• Pete Crow-Armstrong has launched a team-high 28 home runs.
• Crow-Armstrong ranks 21st overall in home runs and 23rd in RBI this year.
• Seiya Suzuki has a team-best 91 runs batted in.
• Happ is hitting .241 with 28 doubles, 21 home runs and 80 walks.

Cubs Team Props

Rays vs. White Sox Highlights | MLB on FOX

Enjoy the best moments between Tampa Bay Rays and the Chicago White Sox.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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