Rays vs. Blue Jays Prediction, Odds, Picks - September 16

The Tampa Bay Rays versus Toronto Blue Jays game on Tuesday at 7:35 p.m. ET will showcase a pair of hot hitters in Junior Caminero and Ernie Clement. The favored Rays have -110 moneyline odds against the underdog Blue Jays, who are listed at -109. Toronto is the run-line favorite (-1.5). An 8-run over/under is set in the game.

Here is everything you need to know from a betting perspective on the Rays-Blue Jays game, regarding the run line, moneyline and total, plus expert picks.

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Orioles vs. Blue Jays Highlights | MLB on FOX

Check out the best moments between the Baltimore Orioles and the Toronto Blue Jays.

Rays vs. Blue Jays Game Information & Odds

• When: Tuesday, September 16, 2025 at 7:35 p.m. ET
• Where: George M. Steinbrenner Field in Tampa, Florida
• How to watch on TV: FDSSUN and SNET

Rays vs. Blue Jays Prediction

• Score Prediction: Rays 5, Blue Jays 4
• Total Prediction: Over 8 runs
• Win Probabilities: Rays 51%, Blue Jays 49%

Rays vs. Blue Jays Betting Insights

• This season, the Rays have been favored 76 times and won 44, or 57.9%, of those games.
• Tampa Bay has a record of 44-33 in games when oddsmakers favor them by at least -110 on the moneyline.
• The Rays have a 52.4% chance to win this game based on the implied probability of the moneyline.
• The Blue Jays have been chosen as underdogs in 72 games this year and have walked away with the win 41 times (56.9%) in those games.
• Toronto has a mark of 40-30 in contests where bookmakers favor it by -109 or worse on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that the Blue Jays have a 52.2% chance of pulling out a win.

Rays Recent Betting Performance

• The Rays have a 2-5 record from the seven games they were moneyline favorites over their last 10 matchups.
• Over their last 10 outings, the Rays and their opponents combined to go over the run total five times (all 10 of the games had set totals).
• The Rays have a 2-8-0 record against the spread over their past 10 games.

Rays Recent Stats

Rays Player Insights

• Caminero has gone yard 44 times in the 2025 campaign while knocking in 108 runs, both totals that lead the Rays.
• Of all hitters in MLB, Caminero is sixth in home runs and fifth in RBI.
• Yandy Diaz is batting .295 to lead his team.
• Diaz ranks 47th in home runs and 37th in RBI among all hitters in the majors.
• Diaz carries a three-game streak with at least one hit into this contest. During his last five outings he is batting .421 with a double, two home runs, five walks and three RBIs.
• Brandon Lowe has 18 doubles, 28 home runs and 36 walks while hitting .256.
• Chandler Simpson has 11 doubles, three triples and 19 walks while batting .291.

Rays Team Props

Blue Jays Recent Betting Performance

• The Blue Jays have played as underdogs in three of their past 10 games and won one of those contests.
• When it comes to hitting the over, the Blue Jays and their opponents are 2-8-0 in their last 10 games with a total.
• The Blue Jays have won five of their last 10 games against the spread.

Blue Jays Recent Stats

Blue Jays Player Insights

• Vladimir Guerrero Jr. has 33 doubles, 23 home runs and 80 walks while batting .301.
• Among all hitters in the majors, Guerrero ranks 52nd in home runs and 37th in RBI.
• George Springer has shown off his power as he paces his team with 29 home runs.
• Among all MLB batters, Springer ranks 21st in homers and 50th in RBI.
• Clement is batting .279 with 31 doubles, two triples, nine home runs and 24 walks.
• Alejandro Kirk is batting .291 with 17 doubles, 12 home runs and 45 walks.

Blue Jays Team Props

Orioles vs. Blue Jays Highlights | MLB on FOX

Check out the best moments between the Baltimore Orioles and the Toronto Blue Jays.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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