Rays vs. Astros Prediction, Odds, Picks - May 20

Jeremy Pena and the Houston Astros hit the field on Tuesday at George M. Steinbrenner Field against Zack Littell, who is the named starter for the Tampa Bay Rays. First pitch will be at 7:05 p.m. ET for the second game of a three-game series. The Rays have been listed as -138 moneyline favorites for this matchup with the Astros (+116). Tampa Bay is favored on the run line (-1.5). The game's total is set at 9 runs.

Take a look at everything you need from a betting perspective on the Rays-Astros game, regarding the run line, moneyline and total, plus expert picks.

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Astros vs. Rays Highlights | MLB on FOX

Check out the top moments from this MLB game between the Houston Astros and the Tampa Bay Rays!

Rays vs. Astros Game Information & Odds

• When: Tuesday, May 20, 2025 at 7:05 p.m. ET
• Where: George M. Steinbrenner Field in Tampa, Florida
• How to watch on TV: FDSSUN and SCHN

Rays vs. Astros Prediction

• Score Prediction: Astros 5, Rays 4
• Total Prediction: Under 9 runs
• Win Probabilities: Rays 51%, Astros 49%

Rays vs. Astros Betting Insights

• The Rays have won 11, or 42.3%, of the 26 games they've played as favorites this season.
• Tampa Bay has a record of 7-9, a 43.8% win rate, when favored by -138 or more by bookmakers this season.
• Sportsbooks have implied with the moneyline set for this matchup that the Rays have a 58% chance to win.
• The Astros have been victorious in seven, or 46.7%, of the 15 contests they have been chosen as underdogs in this season.
• This season, Houston has come away with a win three times in four chances when named as an underdog of at least +116 or longer on the moneyline.
• The moneyline set for this matchup implies the Astros have a 46.3% chance of coming away with a victory in the contest.

Rays Recent Betting Performance

• The Rays have a 2-4 record from the six games they were favored on the moneyline over their last 10 matchups.
• In their last 10 outings, the Rays and their opponents combined to go over the run total three times (all 10 of the games had set totals).
• The Rays are 4-6-0 against the spread over their past 10 games.

Rays Recent Stats

Rays Player Insights

• Yandy Diaz is the Rays RBI leader this season, driving in 24 runs to go with his six home runs and .249 batting average.
• In all of Major League Baseball, Diaz is 80th in home runs and 63rd in RBI.
• Diaz has collected a hit in four games in a row. During his last five outings he is batting .286 with a double and four RBIs.
• Jonathan Aranda has a club-high .309 batting average.
• Aranda is 80th in home runs and 92nd in RBI in the majors.
• Junior Caminero has hit a team-high eight home runs.
• Brandon Lowe has made the most of his opportunities as he paces his team with 24 RBI.
• Lowe takes a three-game streak with at least one hit into this one. During his last five outings he is hitting .300 with two home runs, two walks and four RBIs.

Rays Team Props

Astros Recent Betting Performance

• In four games as underdogs over the last 10 matchups, the Astros have a record of 2-2.
• In their last 10 games with a total, the Astros and their opponents are 3-7-0 when it comes to hitting the over.
• The Astros have a record of 4-6-0 ATS over their last 10 games.

Astros Recent Stats

Astros Player Insights

• Pena leads the Astros with a team-leading batting average of .309.
• Pena is 80th in home runs and 73rd in RBI among all hitters in the big leagues.
• Isaac Paredes has been a reliable source of runs this year, leading the lineup with seven home runs and 24 runs batted in.
• Paredes is 62nd overall in home runs and 63rd in RBI this year.
• Jake Meyers is batting .301 with six doubles, a triple, three home runs and 15 walks.
• Jose Altuve is hitting .236 with six doubles, four home runs and 14 walks.

Astros Team Props

Astros vs. Rays Highlights | MLB on FOX

Check out the top moments from this MLB game between the Houston Astros and the Tampa Bay Rays!

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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