Pirates vs. Nationals Prediction, Odds, Picks - April 17

The Pittsburgh Pirates versus Washington Nationals game on Thursday at 12:35 p.m. ET will showcase a pair of hot hitters in Oneil Cruz and James Wood. The Pirates are -150 moneyline favorites in this matchup against the Nationals (+126). Pittsburgh is the run-line favorite (-1.5). The over/under is 8 runs for this matchup.

Take a look at everything you need from a betting perspective on the Pirates-Nationals game, regarding the run line, moneyline and total, plus expert picks.

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Nationals vs. Pirates Highlights | MLB on FOX

Check out the best moments between the Washington Nationals and the Pittsburgh Pirates.

Pirates vs. Nationals Game Information & Odds

• When: Thursday, April 17, 2025 at 12:35 p.m. ET
• Where: PNC Park in Pittsburgh, Pennsylvania
• How to watch on TV: SportsNet PT and MASN

Pirates vs. Nationals Prediction

• Score Prediction: Pirates 5, Nationals 4
• Total Prediction: Over 8 runs
• Win Probabilities: Pirates 53%, Nationals 47%

Pirates vs. Nationals Betting Insights

• This season, the Pirates have won four out of the eight games in which they've been favored.
• Pittsburgh has played as favorites of -150 or more twice this season and split those games.
• The moneyline for this contest implies a 60% chance of a victory for the Pirates.
• The Nationals have been chosen as underdogs in 15 games this year and have walked away with the win six times (40%) in those games.
• Washington has a win-loss record of 3-7 when favored by +126 or worse by sportsbooks this year.
• Sportsbooks have implied with the moneyline set for this matchup that the Nationals have a 44.2% chance of pulling out a win.

Pirates Recent Betting Performance

• The Pirates have a 2-2 record across the four games they were a moneyline favorite in their last 10 matchups.
• Over their last 10 matchups (all 10 of them had set totals), the Pirates and their opponents combined to hit the over four times.
• The Pirates have a 5-5-0 record against the spread over their past 10 games.

Pirates Recent Stats

Pirates Player Insights

• Cruz is the Pirates best power hitter, launching three long balls this season in addition to accumulating nine RBI, both team highs.
• Cruz's home runs rank him 52nd in the majors, and he ranks 74th in RBI.
• Ke'Bryan Hayes is hitting .203 with a double, a triple, a home run and seven walks.
• Hayes ranks 140th in homers and 91st in RBI in the majors.
• Isiah Kiner-Falefa paces the Pirates with a .267 batting average.
• Andrew McCutchen has two doubles, a home run and six walks while hitting .250.

Pirates Team Props

Nationals Recent Betting Performance

• In eight games as underdogs over the last 10 matchups, the Nationals have a record of 4-4.
• In their last 10 games with a total, the Nationals and their opponents have combined to hit the over eight times.
• The Nationals are 7-3-0 ATS over their last 10 games.

Nationals Recent Stats

Nationals Player Insights

• Wood leads the Nationals with six long balls.
• Wood is fourth in homers and 20th in RBI among all hitters in MLB.
• Keibert Ruiz has a club-best .317 batting average.
• Ruiz is 96th among all hitters in the big leagues in home runs, and 35th in RBI.
• Alex Call is batting .297 with two doubles, a triple and 10 walks.
• Nate Lowe has recorded a team-leading 16 runs batted in.

Nationals Team Props

Nationals vs. Pirates Highlights | MLB on FOX

Check out the best moments between the Washington Nationals and the Pittsburgh Pirates.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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