Padres vs. Red Sox Prediction, Odds, Picks - August 10

A couple of hot hitters, Manny Machado and Jarren Duran, will be on display when the San Diego Padres face the Boston Red Sox on Sunday at 4:10 p.m. ET, at PETCO Park. The Padres are the favorite in this one, at -137, while the underdog Red Sox have +116 odds to play spoiler. San Diego (-1.5) is the favorite on the run line. The over/under is 7.5 runs for this matchup (with -119 odds to go over and -101 odds on the under).

Here is everything you need from a betting perspective on the Padres-Red Sox game, regarding the run line, moneyline and total, plus expert picks.

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Red Sox vs. Padres Highlights | MLB on FOX

Check out the best highlights between the Boston Red Sox and San Diego Padres.

Padres vs. Red Sox Game Information & Odds

• When: Sunday, August 10, 2025 at 4:10 p.m. ET
• Where: PETCO Park in San Diego, California
• How to watch on TV: SDPA and NESN

Padres vs. Red Sox Prediction

• Score Prediction: Padres 5, Red Sox 4
• Total Prediction: Over 7.5 runs
• Win Probabilities: Padres 51%, Red Sox 49%

Padres vs. Red Sox Betting Insights

• The Padres have been favorites in 64 games this season and won 38 (59.4%) of those contests.
• San Diego has a record of 24-15 in games when bookmakers favor them by at least -137 on the moneyline.
• Oddsmakers have implied with the moneyline set for this matchup that the Padres have a 57.8% chance to win.
• The Red Sox have been victorious in 21, or 47.7%, of the 44 contests they have been chosen as underdogs in this season.
• This year, Boston has won eight of 19 games when listed as at least +116 or worse on the moneyline.
• The moneyline set for this matchup implies the Red Sox have a 46.3% chance of walking away with the win.

Padres Recent Betting Performance

• The Padres played as the moneyline favorite for nine of their last 10 games, and went 6-3 in those matchups.
• In their last 10 matchups (all had set totals), the Padres combined with their opponents to hit the over on the total five times.
• The Padres' ATS record is 5-5-0 over their past 10 games.

Padres Recent Stats

Padres Player Insights

• Not only does Machado lead the Padres in hitting with his .297 average, he also paces the squad with 20 home runs and 72 RBI.
• Among all batters in MLB, Machado is 35th in home runs and 19th in RBI.
• Fernando Tatis Jr. is batting .259 with 19 doubles, two triples, 17 home runs and 65 walks.
• Tatis is 61st in homers in the majors, and 117th in RBI.
• Luis Arraez has 22 doubles, four triples, six home runs and 24 walks while hitting .294.
• Arraez has at least one base hit in two games in a row. In his last five games he is batting .217 with a double, two walks and an RBI.
• Xander Bogaerts is hitting .271 with 25 doubles, 10 home runs and 46 walks.

Padres Team Props

Red Sox Recent Betting Performance

• The Red Sox have played as underdogs in five of their past 10 games and won four of those contests.
• In their last 10 games with a total, the Red Sox and their opponents have failed to hit the over twice.
• The Red Sox have a record of 9-1-0 ATS over their last 10 games.

Red Sox Recent Stats

Red Sox Player Insights

• Duran leads the team in batting average with a high-water mark of .266.
• Duran is 119th in home runs and 33rd in RBI among all hitters in MLB.
• Duran has collected a hit in five straight games. During his last five outings he is hitting .350 with a double, a home run, two walks and five RBIs.
• Ceddanne Rafaela has 23 doubles, three triples, 14 home runs and 19 walks while hitting .262.
• Rafaela is 93rd in homers and 83rd in RBI among all hitters in the big leagues.
• Trevor Story paces the Red Sox with 73 runs batted in.
• Wilyer Abreu leads the Red Sox with 21 home runs.

Red Sox Team Props

Red Sox vs. Padres Highlights | MLB on FOX

Check out the best highlights between the Boston Red Sox and San Diego Padres.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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