Mariners vs. Guardians Prediction, Odds, Picks - August 29

The Seattle Mariners and Cleveland Guardians will send George Kirby and Logan Allen, respectively, to the mound when the two squads play on Friday at Progressive Field, at 7:10 p.m. ET. The Guardians have been listed as +135 moneyline underdogs in this matchup against the favorite Mariners (-161). Seattle is a 1.5-run favorite (at +110 odds). The over/under for the contest is listed at 8 runs.

Here's everything you need to know from a betting perspective on the Mariners-Guardians game, regarding the run line, moneyline and total, plus expert picks.

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Rays vs. Guardians Highlights | MLB on FOX

Check out the best moments between the Tampa Bay Rays and Cleveland Guardians.

Mariners vs. Guardians Game Information & Odds

• When: Friday, August 29, 2025 at 7:10 p.m. ET
• Where: Progressive Field in Cleveland, Ohio
• How to watch on TV: MLB Network, CLEG, and ROOT Sports NW

Mariners vs. Guardians Prediction

• Score Prediction: Guardians 6, Mariners 5
• Total Prediction: Over 8 runs
• Win Probabilities: Mariners 50%, Guardians 50%

Mariners vs. Guardians Betting Insights

• The Mariners have entered the game as favorites 92 times this season and won 51, or 55.4%, of those games.
• Seattle has entered 28 games this season favored by -161 or more and is 18-10 in those contests.
• Oddsmakers have implied with the moneyline set for this matchup that the Mariners have a 61.7% chance to win.
• The Guardians have won in 31, or 43.1%, of the 72 contests they have been named as odds-on underdogs this year.
• Cleveland has a mark of 8-14 in contests where oddsmakers favor it by +135 or worse on the moneyline.
• The moneyline set for this matchup implies the Guardians have a 42.6% chance of coming away with a victory in the contest.

Mariners Recent Betting Performance

• The Mariners played as the moneyline favorite for seven of their last 10 games, and finished 4-3 in those matchups.
• Over their last 10 matchups (all 10 of them had set totals), the Mariners and their opponents combined to hit the over seven times.
• The Mariners' record against the spread is 3-7-0 over their past 10 games.

Mariners Recent Stats

Mariners Player Insights

• Cal Raleigh is the Mariners best power option, crushing 50 long balls this season in addition to collecting 107 RBI, both team highs.
• Raleigh's home runs put him first in MLB, and he is third in RBI.
• Julio Rodriguez is hitting .263 with 24 doubles, four triples, 25 home runs and 34 walks.
• Rodriguez is 30th in homers and 38th in RBI among all hitters in MLB.
• Rodriguez carries a four-game streak with at least one hit into this matchup. During his last five outings he is batting .316 with two walks and two RBIs.
• Josh Naylor has a team-high batting average of .286.
• Naylor will look to build on his six-game hitting in this matchup. In his last 10 outings he is hitting .250 with two doubles, a home run, two walks and four RBIs.
• Eugenio Suarez is hitting .237 with 23 doubles, 42 home runs and 37 walks.
• Suarez has recorded at least one hit in two games in a row. In his last five games he is batting .200 with two home runs, five walks and six RBIs.

Mariners Team Props

Guardians Recent Betting Performance

• In seven games as underdogs over the last 10 matchups, the Guardians have a record of 2-5.
• In their last 10 games with a total, the Guardians and their opponents are 3-5-2 when it comes to hitting the over.
• The Guardians have a record of 5-5-0 ATS over their last 10 games.

Guardians Recent Stats

Guardians Player Insights

• Jose Ramirez leads the Guardians with 26 home runs and 68 runs batted in, while posting a team-high batting average of .284.
• In all of the big leagues, Ramirez ranks 22nd in home runs and 53rd in RBI.
• Steven Kwan has 22 doubles, a triple, 10 home runs and 45 walks while batting .271.
• Kwan is currently 178th in home runs and 184th in RBI in the major leagues.
• Kyle Manzardo has 14 doubles, two triples, 21 home runs and 40 walks while batting .231.
• Angel Martinez is batting .225 with 21 doubles, a triple, 10 home runs and 16 walks.

Guardians Team Props

Rays vs. Guardians Highlights | MLB on FOX

Check out the best moments between the Tampa Bay Rays and Cleveland Guardians.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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