Guardians vs. Rays Prediction, Odds, Picks - August 26

Parker Messick and Shane Baz will each get the start when the Cleveland Guardians and the Tampa Bay Rays face off on Tuesday at Progressive Field, at 6:40 p.m. ET. The Guardians have been listed as -118 moneyline favorites for this matchup against the Rays (-102). Cleveland (-1.5) is the favorite on the run line. A 7.5-run total has been set for this game.

Take a look at everything you need from a betting perspective on the Guardians-Rays game, regarding the run line, moneyline and total, plus expert picks.

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Rays vs. Guardians Highlights | MLB on FOX

Check out the best moments between the Tampa Bay Rays and the Cleveland Guardians.

Guardians vs. Rays Game Information & Odds

• When: Tuesday, August 26, 2025 at 6:40 p.m. ET
• Where: Progressive Field in Cleveland, Ohio
• How to watch on TV: CLEG and FDSSUN

Guardians vs. Rays Prediction

• Score Prediction: Rays 5, Guardians 4
• Total Prediction: Under 7.5 runs
• Win Probabilities: Guardians 50%, Rays 50%

Guardians vs. Rays Betting Insights

• This season, the Guardians have won 33 out of the 56 games, or 58.9%, in which they've been favored.
• This season Cleveland has won 29 of its 47 games, or 61.7%, when favored by at least -118 on the moneyline.
• The Guardians have a 54.1% chance to win this game based on the implied probability of the moneyline.
• The Rays have been underdogs in 67 games this season and have come away with the win 27 times (40.3%) in those contests.
• Tampa Bay has a mark of 22-30 in contests where oddsmakers favor it by -102 or worse on the moneyline.
• Oddsmakers have implied with the moneyline set for this matchup that the Rays have a 50.5% chance of pulling out a win.

Guardians Recent Betting Performance

• The Guardians were the moneyline favorite three times in the last 10 games, but they lost every matchup.
• In their last 10 matchups, the Guardians and their opponents combined to go over the total four times (all 10 games had set totals).
• The Guardians are 3-7-0 against the spread over their past 10 games.

Guardians Recent Stats

Guardians Player Insights

• Jose Ramirez leads the Guardians with 26 home runs and 68 runs batted in, while putting up a team-best batting average of .286.
• Among all hitters in MLB, Ramirez's home run total ranks him 19th, and his RBI tally ranks him 50th.
• Steven Kwan is batting .271 with 22 doubles, a triple, 10 home runs and 43 walks.
• Kwan ranks 173rd in homers and 185th in RBI on the season.
• Carlos Santana is batting .225 with 10 doubles, 11 home runs and 52 walks.
• Kyle Manzardo has 14 doubles, two triples, 21 home runs and 40 walks while batting .231.

Guardians Team Props

Rays Recent Betting Performance

• In five games over the last 10 matchups when set as underdogs by sportsbooks, the Rays had a record of 2-3.
• In their last 10 games with a total, the Rays and their opponents have failed to hit the over twice.
• The Rays have five wins against the spread in their last 10 chances.

Rays Recent Stats

Rays Player Insights

• Junior Caminero has a team-high 39 home runs and has driven in 94 runs.
• Among all hitters in MLB, Caminero's home run total ranks sixth and his RBI tally ranks sixth.
• Caminero brings a hitting streak of five games into this game. In his last five games he is batting .381 with a double, four home runs, two walks and nine RBIs.
• Yandy Diaz has 23 doubles, a triple, 22 home runs and 40 walks while hitting .280.
• Diaz is 38th in homers and 29th in RBI among all batters in the big leagues.
• Brandon Lowe is hitting .266 with 13 doubles, 25 home runs and 32 walks.
• Chandler Simpson has 11 doubles, three triples and 18 walks while hitting .302.

Rays Team Props

Rays vs. Guardians Highlights | MLB on FOX

Check out the best moments between the Tampa Bay Rays and the Cleveland Guardians.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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Cleveland Guardians

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