Guardians vs. Marlins Prediction, Odds, Picks - August 13

Steven Kwan and the Cleveland Guardians will play Xavier Edwards and the Miami Marlins on Wednesday at Progressive Field, at 6:40 p.m. ET. The Guardians are listed as -134 moneyline favorites in this matchup against the Marlins (+113). Cleveland is a 1.5-run favorite (at +158 odds). The total is 8 runs for this contest.

Check out everything you need to know from a betting perspective on the Guardians-Marlins game, regarding the run line, moneyline and total, plus expert picks.

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Marlins vs. Guardians Highlights | MLB on FOX

Check out the best moments between the Miami Marlins and the Cleveland Guardians.

Guardians vs. Marlins Game Information & Odds

• When: Wednesday, August 13, 2025 at 6:40 p.m. ET
• Where: Progressive Field in Cleveland, Ohio
• How to watch on TV: CLEG and FDSFL

Guardians vs. Marlins Prediction

• Score Prediction: Guardians 5, Marlins 4
• Total Prediction: Over 8 runs
• Win Probabilities: Guardians 54%, Marlins 46%

Guardians vs. Marlins Betting Insights

• This season, the Guardians have been favored 51 times and won 32, or 62.7%, of those games.
• Cleveland has a record of 19-7, a 73.1% win rate, when favored by -134 or more by sportsbooks this season.
• The moneyline for this contest implies a 57.3% chance of a victory for the Guardians.
• The Marlins have won in 48, or 48%, of the 100 contests they have been named as odds-on underdogs this year.
• This season, Miami has come away with a win 37 times in 76 chances when named as an underdog of at least +113 or longer on the moneyline.
• The moneyline set for this matchup implies the Marlins have a 46.9% chance of walking away with the win.

Guardians Recent Betting Performance

• The Guardians were the moneyline favorite in seven of their last 10 games, and they went 5-2 in those matchups.
• In their last 10 matchups, the Guardians and their opponents combined to go over the run total five times (all 10 games had set totals).
• The Guardians' record against the spread is 5-5-0 over their past 10 games.

Guardians Recent Stats

Guardians Player Insights

• Jose Ramirez's 25 homers and 63 RBI both lead the Guardians, in addition to his team-high .294 average.
• Among all batters in MLB, Ramirez's home run total places him 15th, and his RBI tally ranks him 51st.
• Kwan has 21 doubles, a triple, nine home runs and 41 walks while hitting .275.
• Kwan is 176th in homers and 168th in RBI in the majors.
• Carlos Santana is hitting .227 with nine doubles, 11 home runs and 50 walks.
• Kyle Manzardo is hitting .244 with 14 doubles, two triples, 21 home runs and 36 walks.
• Manzardo is riding a five-game hitting streak into this one. In his last five games he is batting .438 with a double, three home runs, three walks and five RBIs.

Guardians Team Props

Marlins Recent Betting Performance

• The Marlins have played as underdogs in five of their past 10 games and won one of those contests.
• In their last 10 games with a total, the Marlins and their opponents are 6-4-0 when it comes to hitting the over.
• The Marlins have a record of 4-6-0 ATS over their last 10 games.

Marlins Recent Stats

Marlins Player Insights

• Kyle Stowers has posted a team-leading 25 home runs and has driven in 71 runs.
• In all of MLB, Stowers ranks 15th in homers and 22nd in RBI.
• Edwards' .302 batting average is a team-high mark.
• Edwards is 412th in homers and 203rd in RBI among all hitters in the majors.
• Otto Lopez has 15 doubles, 11 home runs and 38 walks while batting .242.
• Agustin Ramirez is hitting .236 with 24 doubles, a triple, 17 home runs and 24 walks.

Marlins Team Props

Marlins vs. Guardians Highlights | MLB on FOX

Check out the best moments between the Miami Marlins and the Cleveland Guardians.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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