Giants vs. Diamondbacks Prediction, Odds, Picks - September 8

Jung Hoo Lee and Corbin Carroll will be among the stars on display when the San Francisco Giants face the Arizona Diamondbacks on Monday at 9:45 p.m. ET, at Oracle Park. The Giants are favored in this one, at -183, while the underdog Diamondbacks have +152 odds to win. San Francisco is the run-line favorite (-1.5). The over/under for the matchup is set at 7.5 runs.

Check out everything you need from a betting perspective on the Giants-Diamondbacks game, regarding the run line, moneyline and total, plus expert picks.

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Giants vs. Diamondbacks Game Information & Odds

• When: Monday, September 8, 2025 at 9:45 p.m. ET
• Where: Oracle Park in San Francisco, California
• How to watch on TV: Fox Sports 1, NBCS-BA, and ARID

Giants vs. Diamondbacks Prediction

• Score Prediction: Giants 5, Diamondbacks 4
• Total Prediction: Over 7.5 runs
• Win Probabilities: Giants 53%, Diamondbacks 47%

Giants vs. Diamondbacks Betting Insights

• This season, the Giants have been favored 83 times and won 44, or 53%, of those games.
• San Francisco has entered 16 games this season favored by -183 or more and is 10-6 in those contests.
• The moneyline for this contest implies a 64.7% chance of a victory for the Giants.
• The Diamondbacks have been chosen as underdogs in 59 games this year and have walked away with the win 29 times (49.2%) in those games.
• Arizona has a win-loss record of 2-3 when favored by +152 or worse by oddsmakers this year.
• The Diamondbacks have an implied victory probability of 39.7% according to the moneyline set by oddsmakers for this matchup.

Giants Recent Betting Performance

• The Giants were the moneyline favorite in seven of their last 10 games, and they went 6-1 in those matchups.
• In their last 10 matchups, the Giants and their opponents combined to go over the run total six times (all 10 of the games had set totals).
• The Giants' record against the spread is 8-2-0 over their past 10 games.

Giants Recent Stats

Giants Player Insights

• Rafael Devers leads the Giants in home runs (31) and runs batted in (100).
• Of all batters in baseball, Devers' home run total ranks him 11th, and his RBI tally puts him seventh.
• Lee has a club-high .267 batting average.
• Lee ranks 247th in homers and 152nd in RBI among all MLB hitters this year.
• Willy Adames is batting .228 with 18 doubles, two triples, 27 home runs and 68 walks.
• Heliot Ramos is hitting .267 to pace his team.

Giants Team Props

Diamondbacks Recent Betting Performance

• In six games over the last 10 matchups when set as underdogs by oddsmakers, the Diamondbacks had a record of 5-1.
• In their last 10 games with a total, the Diamondbacks and their opponents are 4-5-1 when it comes to hitting the over.
• The Diamondbacks are 8-2-0 ATS over their last 10 games.

Diamondbacks Recent Stats

Diamondbacks Player Insights

• Geraldo Perdomo has put up a team-high batting average of .284 while leading the Diamondbacks in runs batted in with a mark of 91.
• Among all batters in MLB, Perdomo's home run total ranks 95th and his RBI tally is 15th.
• Carroll's 30 home runs are a team-high total.
• Carroll ranks 12th overall in home runs and 47th in RBI this year.
• Ketel Marte has 22 doubles, 25 home runs and 63 walks while hitting .283.
• Gabriel Moreno has 11 doubles, a triple, seven home runs and 17 walks while hitting .277.

Diamondbacks Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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