Giants vs. Angels Prediction, Odds, Picks - April 18

Tyler John Anderson gets the nod on the mound for the Los Angeles Angels in the first of a three-game series against the San Francisco Giants and Jung Hoo Lee on Friday at 9:38 p.m. ET. The Giants are listed as -155 moneyline favorites for this matchup with the Angels (+130). San Francisco is favored on the run line (-1.5). The over/under for the matchup has been set at 8 runs.

Check out everything you need to know from a betting perspective on the Giants-Angels game, regarding the run line, moneyline and total, plus expert picks.

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Giants vs. Angels Game Information & Odds

• When: Friday, April 18, 2025 at 9:38 p.m. ET
• Where: Angel Stadium in Anaheim, California
• How to watch on TV: FDSW and NBCS-BA

Giants vs. Angels Prediction

• Score Prediction: Giants 4, Angels 3
• Total Prediction: Under 8 runs
• Win Probabilities: Giants 59%, Angels 41%

Giants vs. Angels Betting Insights

• This season, the Giants have been favored eight times and won six of those games.
• San Francisco has played as favorites of -155 or more once this season and lost that game.
• Bookmakers have implied with the moneyline set for this matchup that the Giants have a 60.8% chance to win.
• The Angels have won in seven, or 50%, of the 14 contests they have been named as odds-on underdogs this year.
• This season, Los Angeles has come away with a win three times in five chances when named as an underdog of at least +130 or longer on the moneyline.
• The Angels have an implied victory probability of 43.5% according to the moneyline set by sportsbooks for this matchup.

Giants Recent Betting Performance

• The Giants have a 1-2 record from the three games they were favored on the moneyline over their last 10 matchups.
• Over their last 10 matchups, the Giants and their opponents combined to go over the run total eight times (all 10 of the games had set totals).
• The Giants' ATS record is 5-5-0 over their past 10 games.

Giants Recent Stats

Giants Player Insights

• Lee's .348 average leads the Giants this year. His resume also includes three homers and driven in 14 RBI.
• Among all MLB hitters, Lee ranks fifth in batting average, 17th in on-base percentage, and fifth in slugging.
• Lee brings a hitting streak of three games into this game. In his last five games he is batting .389 with two doubles, two home runs, a walk and seven RBI.
• Wilmer Flores has hit six home runs with 23 RBI. Both are team-highs.
• Flores is fourth in home runs and first in RBI on the season.
• Mike Yastrzemski has five doubles, three home runs and 12 walks while batting .302.
• Matt James Chapman has three doubles, three home runs and 16 walks while hitting .239.
• Chapman has recorded at least one hit in four games in a row. During his last five outings he is batting .389 with a double, a home run, four walks and four RBI.

Giants Team Props

Angels Recent Betting Performance

• The Angels have played as underdogs in nine of their past 10 games and won four of those contests.
• In their last 10 games with a total, the Angels and their opponents have combined to hit the over four times.
• The Angels have five wins against the spread in their last 10 chances.

Angels Recent Stats

Angels Player Insights

• Kyren Paris is batting .326 with a double, a triple, five home runs and five walks.
• Paris ranks 18th in homers and 100th in RBI among all hitters in MLB.
• Mike Trout been a consistent power bat this season, as he leads his team with six home runs and 14 runs batted in.
• Among all MLB hitters, Trout ranks fourth in homers and 19th in RBI.
• Taylor Ward has three doubles, five home runs and four walks while hitting .237.
• Nolan Schanuel paces the Angels with a team-leading batting average of .279.

Angels Team Props

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