Dodgers vs. Giants Prediction, Odds, Picks - September 20

The Los Angeles Dodgers and Shohei Ohtani will hit the field against the San Francisco Giants and Jung Hoo Lee on Saturday at 9:10 p.m. ET, in the third game of a four-game series at Dodger Stadium. The Giants are +150 moneyline underdogs in this matchup against the favorite Dodgers (-178). Los Angeles is favored on the run line (-1.5). A 9-run total has been set in the contest.

Here's everything you need to know from a betting perspective on the Dodgers-Giants game, regarding the run line, moneyline and total, plus expert picks.

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Dodgers vs. Giants Game Information & Odds

• When: Saturday, September 20, 2025 at 9:10 p.m. ET
• Where: Dodger Stadium in Los Angeles, California
• How to watch on TV: SportsNet LA and NBCS-BA

Dodgers vs. Giants Prediction

• Score Prediction: Dodgers 4, Giants 3
• Total Prediction: Under 9 runs
• Win Probabilities: Dodgers 56%, Giants 44%

Dodgers vs. Giants Betting Insights

• The Dodgers have been favorites in 136 games this season and won 78 (57.4%) of those contests.
• Los Angeles is 45-27 this season when entering a game favored by -178 or more on the moneyline.
• The moneyline for this contest implies a 64% chance of a victory for the Dodgers.
• The Giants have been victorious in 30, or 45.5%, of the 66 contests they have been chosen as underdogs in this season.
• This year, San Francisco has won one of seven games when listed as at least +150 or worse on the moneyline.
• The moneyline set for this matchup implies the Giants have a 40% chance of walking away with the win.

Dodgers Recent Betting Performance

• The Dodgers were the moneyline favorite for nine of their last 10 games, and went 6-3 in those matchups.
• In their last 10 outings (all had set totals), the Dodgers combined with their opponents to hit the over on the total five times.
• The Dodgers are 7-3-0 against the spread over their past 10 games.

Dodgers Recent Stats

Dodgers Player Insights

• Ohtani has accumulated a team-best 52 home runs and 98 runs batted in.
• Ohtani ranks third in home runs and 13th in RBI among all batters in MLB.
• Ohtani has collected a hit in seven straight games. In his last 10 games he is batting .333 with three doubles, four home runs, eight walks and eight RBIs.
• Mookie Betts has 22 doubles, two triples, 20 home runs and 58 walks while batting .260.
• Betts is 73rd in homers and 48th in RBI on the year.
• Freddie Freeman leads the Dodgers with a team-best batting average of .293.
• Andy Pages has 27 doubles, a triple, 25 home runs and 28 walks while batting .281.

Dodgers Team Props

Giants Recent Betting Performance

• In seven games over the last 10 matchups when set as underdogs by oddsmakers, the Giants had a record of 2-5.
• In their last 10 games with a total, the Giants and their opponents have failed to hit the over six times.
• The Giants have won five of their last 10 games against the spread.

Giants Recent Stats

Giants Player Insights

• Rafael Devers paces the Giants in home runs (31) and runs batted in (104).
• In all of MLB, Devers ranks 14th in homers and eighth in RBI.
• Lee is hitting .261 to lead the lineup.
• Lee ranks 242nd among all hitters in the majors in home runs, and 147th in RBI.
• Willy Adames is batting .226 with 21 doubles, two triples, 28 home runs and 76 walks.
• Matt Chapman is hitting .236 with 21 doubles, two triples, 21 home runs and 68 walks.

Giants Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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