Diamondbacks vs. Guardians Prediction, Odds, Picks - August 18

Corbin Carroll and the Arizona Diamondbacks will hit the field at Chase Field against the Cleveland Guardians and Jose Ramirez on Monday. The favored Diamondbacks have -123 moneyline odds against the underdog Guardians, who are listed at +103. Cleveland is the run-line favorite (-1.5). The total is 9 runs for the contest.

Take a look at everything you need to know from a betting perspective on the Diamondbacks-Guardians game, regarding the run line, moneyline and total, plus expert picks.

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Diamondbacks vs. Guardians Game Information & Odds

• When: Monday, August 18, 2025 at 9:40 p.m. ET
• Where: Chase Field in Phoenix, Arizona
• How to watch on TV: ARID and CLEG

Diamondbacks vs. Guardians Prediction

• Score Prediction: Diamondbacks 6, Guardians 5
• Total Prediction: Over 9 runs
• Win Probabilities: Diamondbacks 53%, Guardians 47%

Diamondbacks vs. Guardians Betting Insights

• This season, the Diamondbacks have won 38 out of the 75 games, or 50.7%, in which they've been favored.
• Arizona has entered 54 games this season favored by -123 or more and is 26-28 in those contests.
• The Diamondbacks have a 55.2% chance to win this game based on the implied probability of the moneyline.
• The Guardians have won in 29, or 44.6%, of the 65 contests they have been named as odds-on underdogs this year.
• This season, Cleveland has come away with a win 20 times in 48 chances when named as an underdog of at least +103 or longer on the moneyline.
• Bookmakers have implied with the moneyline set for this matchup that the Guardians have a 49.3% chance of pulling out a win.

Diamondbacks Recent Betting Performance

• The Diamondbacks were favored on the moneyline in seven of their last 10 games, and they finished 4-3 in those matchups.
• Over their last 10 outings, the Diamondbacks and their opponents combined to go over the run total five times (all 10 of the games had set totals).
• The Diamondbacks have a 6-4-0 record against the spread over their past 10 games.

Diamondbacks Recent Stats

Diamondbacks Player Insights

• Geraldo Perdomo is the Diamondbacks RBI leader this season, driving in 79 runs to go with his 13 home runs and .286 batting average.
• Including all MLB batters, Perdomo is 22nd in batting average, seventh in on-base percentage, and 75th in slugging.
• Perdomo has collected a hit in two games in a row. In his last five games he is hitting .278 with a home run, six walks and an RBI.
• Corbin Carroll has hit 27 home runs to lead his team.
• Including all major league hitters, Carroll ranks 11th in home runs and 51st in RBI.
• Carroll has five games in a row with at least one hit. During his last five outings he is batting .300 with a double, a home run, four walks and two RBIs.
• Ketel Marte has accumulated a team-high batting average of .297.
• Lourdes Gurriel Jr. is batting .246 with 23 doubles, two triples, 16 home runs and 29 walks.
• Gurriel has recorded at least one hit in four games in a row. In his last five games he is batting .294 with a double, two home runs, two walks and seven RBIs.

Diamondbacks Team Props

Guardians Recent Betting Performance

• Over the past 10 games, the Guardians have been underdogs just once and won that contest.
• In their last 10 games with a total, the Guardians and their opponents have failed to hit the over five times.
• The Guardians have a record of 5-5-0 ATS over their last 10 games.

Guardians Recent Stats

Guardians Player Insights

• Jose Ramirez paces the Guardians in home runs (25), runs batted in (64) and has posted a team-high batting average of .291.
• Among all hitters in the majors, Ramirez ranks 17th in homers and 51st in RBI.
• Steven Kwan has 22 doubles, a triple, 10 home runs and 42 walks while batting .281.
• Kwan is 157th among all hitters in MLB in home runs, and 171st in RBI.
• Carlos Santana is hitting .227 with nine doubles, 11 home runs and 52 walks.
• Kyle Manzardo has 14 doubles, two triples, 21 home runs and 40 walks while hitting .238.

Guardians Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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Arizona Diamondbacks

Cleveland Guardians