Cubs vs. Reds Prediction, Odds, Picks - August 4

The Cincinnati Reds and Elly De La Cruz take the field at Wrigley Field against Pete Crow-Armstrong and the Chicago Cubs on Monday. The Cubs are favored in this one, at -134, while the underdog Reds have +113 odds to win. Chicago is favored on the run line (-1.5 with +159 odds). A 7-run total is set in the contest.

Here is everything you need from a betting perspective on the Cubs-Reds game, regarding the run line, moneyline and total, plus expert picks.

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Orioles vs. Cubs Highlights | MLB on FOX

Check out the best moments between the Baltimore Orioles and Chicago Cubs.

Cubs vs. Reds Game Information & Odds

• When: Monday, August 4, 2025 at 8:05 p.m. ET
• Where: Wrigley Field in Chicago, Illinois
• How to watch on TV: MARQ and FDSOH

Cubs vs. Reds Prediction

• Score Prediction: Cubs 6, Reds 5
• Total Prediction: Over 7 runs
• Win Probabilities: Cubs 54%, Reds 46%

Cubs vs. Reds Betting Insights

• The Cubs have won 52, or 67.5%, of the 77 games they've played as favorites this season.
• Chicago has a record of 41-17, a 70.7% win rate, when favored by -134 or more by bookmakers this season.
• The moneyline for this contest implies a 57.3% chance of a victory for the Cubs.
• The Reds have come away with 30 wins in the 58 contests they have been listed as the underdogs in this season.
• This season, Cincinnati has been victorious 12 times in 32 chances when named as an underdog of at least +113 or longer on the moneyline.
• Bookmakers have implied with the moneyline set for this matchup that the Reds have a 46.9% chance of pulling out a win.

Cubs Recent Betting Performance

• The Cubs went 4-4 across the eight games they were favored on the moneyline in their last 10 matchups.
• Over their last 10 outings -- all had a set run total -- the Cubs and their opponents combined to hit the over on the total six times.
• The Cubs' ATS record is 3-7-0 over their past 10 games.

Cubs Recent Stats

Cubs Player Insights

• Kyle Tucker is hitting .276 with 21 doubles, four triples, 18 home runs and 74 walks.
• Tucker ranks 45th in home runs and 40th in RBI among all batters in MLB.
• Tucker carries a two-game hitting streak into this matchup. In his last five games he is hitting .313 with a double, four walks and two RBIs.
• Crow-Armstrong has hit 27 home runs to lead his team.
• Crow-Armstrong is seventh in home runs in MLB, and ninth in RBI.
• Seiya Suzuki has accumulated a team-high 82 runs batted in.
• Nico Hoerner is batting .295 to pace his team.
• Hoerner has recorded at least one hit in two straight games. During his last five outings he is hitting .421 with a double, a home run, a walk and four RBIs.

Cubs Team Props

Reds Recent Betting Performance

• In three games as underdogs over the last 10 matchups, the Reds have a record of 1-2.
• In their last 10 games with a total, the Reds and their opponents have combined to hit the over just once.
• The Reds have a record of 6-4-0 ATS over their last 10 games.

Reds Recent Stats

Reds Player Insights

• De La Cruz paces the Reds with 19 home runs and 72 runs batted in, while recording a team-high batting average of .282.
• Among all hitters in the big leagues, De La Cruz's home run total is 36th and his RBI tally ranks 14th.
• TJ Friedl is batting .271 with 16 doubles, two triples, 10 home runs and 54 walks.
• Friedl is 144th among all hitters in the majors in home runs, and 170th in RBI.
• Spencer Steer is batting .238 with 15 doubles, two triples, 12 home runs and 32 walks.
• Matt McLain is hitting .225 with 12 doubles, 11 home runs and 40 walks.

Reds Team Props

Orioles vs. Cubs Highlights | MLB on FOX

Check out the best moments between the Baltimore Orioles and Chicago Cubs.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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