Cubs vs. Padres Prediction, Odds, Picks - April 15

Seiya Suzuki and the Chicago Cubs will square off against Fernando Tatis Jr. and the San Diego Padres at PETCO Park on Tuesday. The Cubs are favored in this one, at -154, while the underdog Padres have +129 odds to upset. Chicago (-1.5) is favored on the run line. The game's over/under is set at 8 runs.

Check out everything you need to know from a betting perspective on the Cubs-Padres game, regarding the run line, moneyline and total, plus expert picks.

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Check out the best highlights between the Chicago Cubs and the Los Angeles Dodgers.

Cubs vs. Padres Game Information & Odds

• When: Tuesday, April 15, 2025 at 9:40 p.m. ET
• Where: PETCO Park in San Diego, California
• How to watch on TV: SDPA and MARQ

Cubs vs. Padres Prediction

• Score Prediction: Padres 4, Cubs 3
• Total Prediction: Under 8 runs
• Win Probabilities: Cubs 55%, Padres 45%

Cubs vs. Padres Betting Insights

• The Cubs have entered the game as favorites eight times this season and won six of those games.
• Chicago has entered three games this season favored by -154 or more and is 2-1 in those contests.
• The Cubs have a 60.6% chance to win this game based on the implied probability of the moneyline.
• The Padres have come away with four wins in the six contests they have been listed as the underdogs in this season.
• San Diego has played as an underdog of +129 or more just one time this year and came away with a loss in that game.
• The moneyline set for this matchup implies the Padres have a 43.7% chance of walking away with the win.

Cubs Recent Betting Performance

• The Cubs were favored on the moneyline for six of their last 10 games, and they finished 4-2 in those matchups.
• Over their last 10 outings, the Cubs and their opponents combined to hit the over on the total seven times (all 10 games had set totals).
• The Cubs' ATS record is 6-4-0 over their past 10 games.

Cubs Recent Stats

Cubs Player Insights

• Kyle Tucker has put up a team-best five home runs and 18 runs batted in.
• Of all hitters in the majors, Tucker's home run total ranks him ninth, and his RBI tally ranks him fourth.
• Carson Kelly has a double, a triple, four home runs and 11 walks while hitting .417.
• Suzuki has two doubles, a triple, four home runs and 11 walks while batting .292.
• Michael Busch's .310 batting average paces his team.
• Busch is riding a three-game hitting streak into this one. During his last five outings he is batting .381 with two doubles, three home runs, a walk and seven RBI.

Cubs Team Props

Padres Recent Betting Performance

• The Padres have played as underdogs in four of their past 10 games and won two of those contests.
• In their last 10 games with a total, the Padres and their opponents have combined to hit the over six times.
• The Padres have a record of 6-4-0 ATS over their last 10 games.

Padres Recent Stats

Padres Player Insights

• Tatis paces the Padres with six home runs and 12 runs batted in, while recording a team-best batting average of .361.
• Among all hitters in the majors, Tatis' home run total ranks first and his RBI tally ranks 16th.
• Tatis takes a hitting streak of four games into this game. During his last five outings he is hitting .316 with four home runs, two walks and five RBI.
• Manny Machado is hitting .317 with seven doubles, a home run and eight walks.
• Machado is 127th in homers and 129th in RBI among all hitters in the majors.
• Luis Arraez is hitting .282 with three doubles, two home runs and two walks.
• Xander Bogaerts has five doubles and nine walks while batting .288.

Padres Team Props

Cubs vs. Dodgers Highlights | MLB on FOX

Check out the best highlights between the Chicago Cubs and the Los Angeles Dodgers.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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