Cubs vs. Angels Prediction, Odds, Picks - August 23

Matt Shaw and the Chicago Cubs will see Victor Mederos on the hill for the Los Angeles Angels in the second game of a three-game series, Saturday at 9:38 p.m. ET. The Angels have been listed as +127 moneyline underdogs in this matchup with the favorite Cubs (-152). Chicago (-1.5) is the favorite on the run line. The over/under is 10 runs for the game (with -105 odds on the over and -115 odds to go under).

Here's everything you need from a betting perspective on the Cubs-Angels game, regarding the run line, moneyline and total, plus expert picks.

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Cubs vs. Angels Highlights | MLB on FOX

Check out the best moments between the Chicago Cubs and Los Angeles Angels.

Cubs vs. Angels Game Information & Odds

• When: Saturday, August 23, 2025 at 9:38 p.m. ET
• Where: Angel Stadium in Anaheim, California
• How to watch on TV: FDSW and MARQ

Cubs vs. Angels Prediction

• Score Prediction: Cubs 6, Angels 5
• Total Prediction: Under 10 runs
• Win Probabilities: Cubs 51%, Angels 49%

Cubs vs. Angels Betting Insights

• The Cubs have entered the game as favorites 91 times this season and won 58, or 63.7%, of those games.
• This season Chicago has won 33 of its 46 games, or 71.7%, when favored by at least -152 on the moneyline.
• The moneyline for this contest implies a 60.3% chance of a victory for the Cubs.
• The Angels have won in 44, or 46.3%, of the 95 contests they have been named as odds-on underdogs this year.
• This season, Los Angeles has been victorious 25 times in 50 chances when named as an underdog of at least +127 or worse on the moneyline.
• Bookmakers have implied with the moneyline set for this matchup that the Angels have a 44.1% chance of pulling out a win.

Cubs Recent Betting Performance

• The Cubs went 4-4 over the eight games they were moneyline favorites in their last 10 matchups.
• Over their last 10 outings (all had set totals), the Cubs combined with their opponents to hit the over on the total two times.
• The Cubs' record against the spread is 4-6-0 over their past 10 games.

Cubs Recent Stats

Cubs Player Insights

• Kyle Tucker is hitting .258 with 21 doubles, four triples, 19 home runs and 80 walks.
• Tucker is 56th in home runs and 60th in RBI among all hitters in baseball.
• Pete Crow-Armstrong's 28 home runs are a team-high mark.
• Crow-Armstrong ranks 10th in home runs and 17th in RBI among all hitters in baseball.
• Seiya Suzuki leads the Cubs with 87 runs batted in.
• Nico Hoerner is batting .288 to pace his team.
• Hoerner has recorded at least one hit in two games in a row. During his last five outings he is hitting .176 with a walk and an RBI.

Cubs Team Props

Angels Recent Betting Performance

• The Angels have played as underdogs in eight of their past 10 games and won four of those contests.
• In their last 10 games with a total, the Angels and their opponents are 6-4-0 when it comes to hitting the over.
• The Angels have five wins against the spread in their last 10 chances.

Angels Recent Stats

Angels Player Insights

• Taylor Ward has put up a team-leading 29 home runs and has driven in 92 runs.
• In all of the majors, Ward is ninth in homers and sixth in RBI.
• Nolan Schanuel is batting .267 to lead the lineup.
• Schanuel is currently 164th in homers and 125th in RBI in the big leagues.
• Zach Neto is batting .265 with 26 doubles, a triple, 21 home runs and 27 walks.
• Jo Adell is batting .233 with 15 doubles, a triple, 28 home runs and 28 walks.

Angels Team Props

Cubs vs. Angels Highlights | MLB on FOX

Check out the best moments between the Chicago Cubs and Los Angeles Angels.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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