Cubs vs. Angels Prediction, Odds, Picks - August 22

A couple of hot hitters, Kyle Tucker and Taylor Ward, will be on display when the Chicago Cubs play the Los Angeles Angels on Friday at 9:38 p.m. ET, at Angel Stadium. The Cubs are -131 moneyline favorites for this matchup against the Angels (+109). Chicago is favored on the run line (-1.5). The total is 9.5 runs for this contest (with -112 odds to hit the over and -108 odds on the under).

Take a look at everything you need to know from a betting perspective on the Cubs-Angels game, regarding the run line, moneyline and total, plus expert picks.

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Cubs vs. Angels Game Information & Odds

• When: Friday, August 22, 2025 at 9:38 p.m. ET
• Where: Angel Stadium in Anaheim, California
• How to watch on TV: FDSW and MARQ

Cubs vs. Angels Prediction

• Score Prediction: Cubs 5, Angels 4
• Total Prediction: Under 9.5 runs
• Win Probabilities: Cubs 51%, Angels 49%

Cubs vs. Angels Betting Insights

• The Cubs have won 57, or 63.3%, of the 90 games they've played as favorites this season.
• This season Chicago has won 46 of its 69 games, or 66.7%, when favored by at least -131 on the moneyline.
• The moneyline for this contest implies a 56.7% chance of a victory for the Cubs.
• The Angels have come away with 44 wins in the 94 contests they have been listed as the underdogs in this season.
• This season, Los Angeles has been victorious 35 times in 79 chances when named as an underdog of at least +109 or worse on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that the Angels have a 47.8% chance of pulling out a win.

Cubs Recent Betting Performance

• The Cubs were favored on the moneyline in seven of their last 10 games, and they finished 3-4 in those matchups.
• Over their last 10 outings (all 10 of them had set totals), the Cubs and their opponents combined to go over the run total two times.
• The Cubs have a 5-5-0 record against the spread over their past 10 games.

Cubs Recent Stats

Cubs Player Insights

• Tucker is hitting .258 with 21 doubles, four triples, 18 home runs and 80 walks.
• Of all batters in baseball, Tucker is 61st in homers and 61st in RBI.
• Pete Crow-Armstrong's 27 home runs are a team-high mark.
• Crow-Armstrong is 13th in home runs and 17th in RBI in the major leagues.
• Seiya Suzuki paces the Cubs with 27 home runs and 86 runs batted in.
• Nico Hoerner's .289 batting average leads his team.

Cubs Team Props

Angels Recent Betting Performance

• In eight games over the last 10 matchups when set as underdogs by bookmakers, the Angels had a record of 4-4.
• When it comes to hitting the over, the Angels and their opponents are 7-3-0 in their last 10 games with a total.
• The Angels have a record of 4-6-0 ATS over their last 10 games.

Angels Recent Stats

Angels Player Insights

• Ward has managed a team-high 29 home runs and has driven in 92 runs.
• Among all hitters in MLB, Ward is eighth in home runs and fifth in RBI.
• Nolan Schanuel's .269 batting average leads his team.
• Schanuel ranks 160th among all hitters in the big leagues in home runs, and 124th in RBI.
• Zach Neto is batting .267 with 26 doubles, a triple, 21 home runs and 27 walks.
• Jo Adell has 15 doubles, a triple, 28 home runs and 28 walks while hitting .232.

Angels Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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