Blue Jays vs. Orioles Prediction, Odds, Picks - September 14

Albert Suarez will look to shut down Vladimir Guerrero Jr. and the Toronto Blue Jays when they play his Baltimore Orioles on Sunday at 1:37 p.m. ET. The Orioles are +171 moneyline underdogs in this matchup against the favored Blue Jays (-207). Toronto is the run-line favorite (-1.5). The over/under is 8 runs for the game (with -110 odds to hit the over and -110 odds on the under).

Here's everything you need to know from a betting perspective on the Blue Jays-Orioles game, regarding the run line, moneyline and total, plus expert picks.

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Blue Jays vs. Orioles Game Information & Odds

• When: Sunday, September 14, 2025 at 1:37 p.m. ET
• Where: Rogers Centre in Toronto, Ontario
• How to watch on TV: SNET and MASN2

Blue Jays vs. Orioles Prediction

• Score Prediction: Blue Jays 6, Orioles 4
• Total Prediction: Over 8 runs
• Win Probabilities: Blue Jays 56%, Orioles 44%

Blue Jays vs. Orioles Betting Insights

• The Blue Jays have been favorites in 74 games this season and won 44 (59.5%) of those contests.
• Toronto has been at least -207 moneyline favorites six times this season and won each of those games.
• The Blue Jays have a 67.4% chance to win this game based on the implied probability of the moneyline.
• The Orioles have won in 38, or 45.8%, of the 83 contests they have been named as odds-on underdogs this year.
• This year, Baltimore has won three of five games when listed as at least +171 or worse on the moneyline.
• The Orioles have an implied victory probability of 36.9% according to the moneyline set for this matchup.

Blue Jays Recent Betting Performance

• The Blue Jays were favored on the moneyline in seven of their last 10 games, and they went 6-1 in those matchups.
• Over their last 10 outings (all 10 of them had set totals), the Blue Jays and their opponents combined to hit the over three times.
• The Blue Jays have gone 6-4-0 against the spread over their past 10 games.

Blue Jays Recent Stats

Blue Jays Player Insights

• Guerrero is batting .305 with 33 doubles, 23 home runs and 79 walks.
• Guerrero is 51st in homers and 35th in RBI among all hitters in the majors.
• Guerrero takes a hitting streak of three games into this game. During his last five outings he is hitting .421 with three walks and an RBI.
• George Springer has shown his power as he leads his team with 28 home runs.
• Springer ranks 22nd in homers and 59th in RBI in the major leagues.
• Springer has three straight games with at least one hit. During his last five outings he is hitting .263 with a home run, three walks and an RBI.
• Ernie Clement is batting .277 with 29 doubles, two triples, nine home runs and 24 walks.
• Clement has at least one base hit in two straight games. During his last five outings he is batting .333 with a double, a walk and an RBI.
• Alejandro Kirk is batting .287 with 17 doubles, 12 home runs and 45 walks.

Blue Jays Team Props

Orioles Recent Betting Performance

• In eight games as underdogs over the last 10 matchups, the Orioles have a record of 5-3.
• In their last 10 games with a total, the Orioles and their opponents are 2-7-1 when it comes to hitting the over.
• The Orioles are 6-4-0 ATS over their last 10 games.

Orioles Recent Stats

Orioles Player Insights

• Gunnar Henderson paces the Orioles with 62 runs batted in while racking up a team-high batting average of .270.
• In all of the majors, Henderson is 112th in homers and 97th in RBI.
• Jackson Holliday has hit a team-high 17 home runs.
• Holliday is 100th among all hitters in the majors in home runs, and 128th in RBI.
• Ryan Mountcastle is batting .256 with 18 doubles, five home runs and 14 walks.
• Colton Cowser is batting .201 with 12 doubles, 13 home runs and 22 walks.

Orioles Team Props

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