Blue Jays vs. Orioles Prediction, Odds, Picks - September 13

Max Scherzer will start for the Toronto Blue Jays on Saturday at Rogers Centre against Jackson Holliday and the Baltimore Orioles. First pitch is at 3:07 p.m. ET for the second game of a three-game series. The favored Blue Jays have -179 moneyline odds to win against the underdog Orioles, who are listed at +149. Toronto (-1.5) is favored on the run line. The over/under for the matchup has been listed at 8.5 runs.

Here is everything you need to know from a betting perspective on the Blue Jays-Orioles game, regarding the run line, moneyline and total, plus expert picks.

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Blue Jays vs. Orioles Game Information & Odds

• When: Saturday, September 13, 2025 at 3:07 p.m. ET
• Where: Rogers Centre in Toronto, Ontario
• How to watch on TV: SNET and MASN2

Blue Jays vs. Orioles Prediction

• Score Prediction: Blue Jays 5, Orioles 4
• Total Prediction: Over 8.5 runs
• Win Probabilities: Blue Jays 57%, Orioles 43%

Blue Jays vs. Orioles Betting Insights

• The Blue Jays have entered the game as favorites 73 times this season and won 43, or 58.9%, of those games.
• Toronto is 11-3 this season when entering a game favored by -179 or more on the moneyline.
• Oddsmakers have implied with the moneyline set for this matchup that the Blue Jays have a 64.2% chance to win.
• The Orioles have been victorious in 38, or 46.3%, of the 82 contests they have been chosen as underdogs in this season.
• This season, Baltimore has come away with a win six times in 13 chances when named as an underdog of at least +149 or worse on the moneyline.
• The Orioles have an implied victory probability of 40.2% according to the moneyline set for this matchup.

Blue Jays Recent Betting Performance

• The Blue Jays have a 5-1 record over the six games they were a moneyline favorite in their last 10 matchups.
• In their last 10 outings (all 10 of them had set totals), the Blue Jays and their opponents combined to hit the over three times.
• The Blue Jays' record against the spread is 7-3-0 over their past 10 games.

Blue Jays Recent Stats

Blue Jays Player Insights

• Vladimir Guerrero Jr. is hitting .305 with 33 doubles, 23 home runs and 78 walks.
• Guerrero is 50th in homers and 33rd in RBI among all hitters in MLB.
• Guerrero carries a two-game hitting streak into this matchup. During his last five outings he is batting .450 with a double, two walks and two RBIs.
• George Springer has put his power on display as he paces his team with 28 home runs.
• Among all major league batters, Springer ranks 21st in home runs and 55th in RBI.
• Springer has two games in a row with at least one hit. During his last five outings he is batting .211 with a double, a home run, three walks and an RBI.
• Ernie Clement is hitting .275 with 29 doubles, two triples, nine home runs and 24 walks.
• Alejandro Kirk is batting .286 with 17 doubles, 12 home runs and 45 walks.

Blue Jays Team Props

Orioles Recent Betting Performance

• In eight games over the last 10 matchups when set as underdogs by oddsmakers, the Orioles had a record of 6-2.
• In their last 10 games with a total, the Orioles and their opponents have combined to hit the over just once.
• The Orioles have a record of 6-4-0 ATS over their last 10 games.

Orioles Recent Stats

Orioles Player Insights

• The Orioles are led in runs batted in by Gunnar Henderson with a mark of 61, he also leads the team in hitting, posting an average of .269.
• Henderson's home run total puts him 111th in MLB, and he is 101st in RBI.
• Holliday has put his power on display as he paces his team with 17 home runs.
• Holliday ranks 100th overall in home runs and 126th in RBI this season.
• Ryan Mountcastle is batting .256 with 18 doubles, five home runs and 14 walks.
• Colton Cowser is batting .204 with 12 doubles, 13 home runs and 22 walks.

Orioles Team Props

Blue Jays vs. Yankees Highlights | MLB on FOX

Check out the best highlights between the Toronto Blue Jays and the New York Yankees.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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