Blue Jays vs. Guardians Prediction, Odds, Picks - May 2

Vladimir Guerrero Jr. and the Toronto Blue Jays will play Steven Kwan and the Cleveland Guardians on Friday at Rogers Centre, at 7:07 p.m. ET. The Guardians are listed as +142 moneyline underdogs for this matchup against the favored Blue Jays (-169). Toronto is the favorite on the run line (-1.5). The total for the contest is set at 8.5 runs.

Check out everything you need to know from a betting perspective on the Blue Jays-Guardians game, regarding the run line, moneyline and total, plus expert picks.

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Blue Jays vs. Guardians Game Information & Odds

• When: Friday, May 2, 2025 at 7:07 p.m. ET
• Where: Rogers Centre in Toronto, Ontario
• How to watch on TV: SN1 and CLEG

Blue Jays vs. Guardians Prediction

• Score Prediction: Blue Jays 4, Guardians 3
• Total Prediction: Under 8.5 runs
• Win Probabilities: Blue Jays 53%, Guardians 47%

Blue Jays vs. Guardians Betting Insights

• This season, the Blue Jays have won five out of the eight games in which they've been favored.
• Toronto has played as favorites of -169 or more once this season and won that game.
• The moneyline for this contest implies a 62.8% chance of a victory for the Blue Jays.
• The Guardians have been victorious in nine, or 47.4%, of the 19 contests they have been chosen as underdogs in this season.
• Cleveland has a mark of 2-2 in contests where sportsbooks favor it by +142 or worse on the moneyline.
• The Guardians have an implied victory probability of 41.3% according to the moneyline set for this matchup.

Blue Jays Recent Betting Performance

• The Blue Jays were listed as the moneyline favorite by oddsmakers just one time in the last 10 games, and lost that matchup.
• In their last 10 matchups (all had set totals), the Blue Jays combined with their opponents to go over the total five times.
• The Blue Jays' ATS record is 3-7-0 over their past 10 games.

Blue Jays Recent Stats

Blue Jays Player Insights

• Guerrero is the Blue Jays best power hitter, hitting four round-trippers this season in addition to delivering 17 RBI, both team highs.
• Guerrero is 76th in homers and 45th in RBI among all hitters in MLB.
• Guerrero takes a hitting streak of four games into this matchup. During his last five outings he is batting .211 with two home runs, a walk and six RBI.
• Bo Bichette is batting .293 with 10 doubles and five walks.
• Bichette is 299th in homers and 107th in RBI among all batters in MLB.
• Bichette has three straight games with at least one hit. During his last five outings he is hitting .300 with two doubles.
• George Springer paces the Blue Jays with a team-best batting average of .306.
• Andres Gimenez has four doubles, three home runs and 10 walks while hitting .165.

Blue Jays Team Props

Guardians Recent Betting Performance

• The Guardians have played as underdogs in seven of their past 10 games and have gone 4-3 in those contests.
• When it comes to hitting the over, the Guardians and their opponents are 5-5-0 in their last 10 games with a total.
• The Guardians have won five of their last 10 games against the spread.

Guardians Recent Stats

Guardians Player Insights

• Kwan leads the Guardians with a .311 batting average.
• Kwan's home run total puts him 76th in MLB, and he ranks 68th in RBI.
• Jose Ramirez is batting .261 with five doubles, five home runs and nine walks.
• Among all MLB hitters, Ramirez is 49th in home runs and 68th in RBI.
• Kyle Manzardo has been a significant run producer for the Guardians with eight home runs and 20 runs batted in.
• Gabriel Arias is batting .255 with six doubles, four home runs and eight walks.

Guardians Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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Toronto Blue Jays

Cleveland Guardians