Angels vs. Athletics Prediction, Odds, Picks - September 5

Jo Adell and the Los Angeles Angels head into the first of a three-game series against Nick Kurtz and the Athletics at Angel Stadium, Friday at 9:38 p.m. ET. The Angels are -153 moneyline favorites in this matchup against the Athletics (+128). The Angels are favored on the run line (-1.5). The over/under is 9 runs for this matchup.

Here is everything you need to know from a betting perspective on the Angels-Athletics game, regarding the run line, moneyline and total, plus expert picks.

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Angels vs. Athletics Game Information & Odds

• When: Friday, September 5, 2025 at 9:38 p.m. ET
• Where: Angel Stadium in Anaheim, California
• How to watch on TV: FDSW and NBCS-CA

Angels vs. Athletics Prediction

• Score Prediction: Angels 6, Athletics 5
• Total Prediction: Over 9 runs
• Win Probabilities: Angels 52%, Athletics 48%

Angels vs. Athletics Betting Insights

• The Angels have entered the game as favorites 33 times this season and won 17, or 51.5%, of those games.
• The Angels have a record of 5-4, a 55.6% win rate, when they're favored by -153 or more by sportsbooks this season.
• The moneyline for this contest implies a 60.5% chance of a victory for the Angels.
• The Athletics have won in 48, or 44.9%, of the 107 contests they have been named as odds-on underdogs this year.
• This season, the Athletics have come away with a win 17 times in 50 chances when named as an underdog of at least +128 or longer on the moneyline.
• The moneyline set for this matchup implies the Athletics have a 43.9% chance of walking away with the win.

Angels Recent Betting Performance

• Over the last 10 games, the Angels have not been the moneyline favorite.
• Over their last 10 outings (all 10 of them had set totals), the Angels and their opponents combined to go over the run total three times.
• The Angels' ATS record is 6-4-0 over their past 10 games.

Angels Recent Stats

Angels Player Insights

• Taylor Ward leads the Angels with 94 runs batted in.
• Of all batters in the majors, Ward is 11th in home runs and 10th in RBI.
• Zach Neto is batting .261 with 29 doubles, a triple, 25 home runs and 31 walks.
• Neto ranks 36th in home runs and 95th in RBI in the majors.
• Adell has hit a team-best 33 homers.
• Mike Trout is hitting .230 with 12 doubles, a triple, 20 home runs and 77 walks.

Angels Team Props

Athletics Recent Betting Performance

• The Athletics have played as underdogs in eight of their past 10 games and won four of those contests.
• In their last 10 games with a total, the Athletics and their opponents are 6-4-0 when it comes to hitting the over.
• The Athletics have a record of 4-6-0 ATS over their last 10 games.

Athletics Recent Stats

Athletics Player Insights

• Brent Rooker is hitting .271 with 37 doubles, three triples, 27 home runs and 56 walks.
• Among all batters in the majors, Rooker's home run total is 24th and his RBI tally ranks 26th.
• Tyler Soderstrom has put up 81 runs batted in to lead his team.
• Soderstrom ranks 43rd overall in home runs and 24th in RBI this season.
• Kurtz is hitting .308 with 24 doubles, two triples, 28 home runs and 54 walks.
• Shea Langeliers paces the Athletics with 29 long balls.

Athletics Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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