Ole Miss vs. Florida Prediction, Odds, Picks - November 15, 2025

Updated Nov. 15, 2025 3:04 p.m. ET

Data Skrive

Oddsmakers heavily favor the No. 6 Ole Miss Rebels (9-1) when they host the Florida Gators (3-6) on Saturday, November 15, 2025 in a matchup between SEC foes at Vaught-Hemingway Stadium. Ole Miss is favored by 11.5 points. The contest has a point total set at 53.5.

The Rebels won against the The Citadel Bulldogs in their most recent game, 49-0. The Gators lost to the Kentucky Wildcats, 38-7, in their last game.

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Ole Miss vs. Florida Game Information & Odds

When: Saturday, November 15, 2025 at 7 p.m. ET
Location: Vaught-Hemingway Stadium in Oxford, Mississippi
TV: ESPN
Live Box Score on FOX Sports

Ole Miss vs Florida Betting Information updated as of November 15, 2025, 2:46 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Ole Miss	-11.5 (-108)	-493	+374	53.5	-110	-110

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Ole Miss vs. Florida Prediction

Pick ATS: Ole Miss (-11.5)
Pick OU: Under (53.5)
Prediction: Ole Miss 32, Florida 17

Predictions are made by the Data Skrive betting model.

Learn more about the Ole Miss Rebels vs. the Florida Gators game on FOX Sports!

Ole Miss vs. Florida Betting Insights

Based on the spread and over/under, the implied score for the tilt is Rebels 32, Gators 21.
The Rebels have an 83.1% chance to win this contest based on the moneyline's implied probability. The Gators have a 21.1% implied probability.
Ole Miss has covered six times in 10 games with a spread this season.
Florida has covered three times in nine matchups with a spread this season.

Ole Miss vs. Florida: 2025 Stats Comparison

	Ole Miss	Florida
Off. Points per Game (Rank)	37.5 (8)	20.4 (119)
Def. Points per Game (Rank)	19.8 (36)	22.4 (42)
Turnovers Allowed (Rank)	10 (41)	16 (114)
Turnovers Forced (Rank)	7 (122)	14 (39)

Ole Miss 2025 Key Players

Name	Position	Stats
Trinidad Chambliss	QB	2,356 YDS (64%) / 13 TD / 2 INT 434 RUSH YDS / 6 RUSH TD / 43.4 RUSH YPG
Kewan Lacy	RB	912 YDS / 16 TD / 91.2 YPG / 4.6 YPC 22 REC / 134 REC YDS / 0 REC TD / 14.9 REC YPG
Harrison Wallace III	WR	36 REC / 579 YDS / 2 TD / 57.9 YPG
Dae'Quan Wright	TE	25 REC / 449 YDS / 4 TD / 44.9 YPG
Suntarine Perkins	LB	45 TKL / 4 TFL / 2 SACK / 1 INT
T.J. Dudley	LB	58 TKL / 2 TFL / 0.5 SACK
Kam Franklin	DL	43 TKL / 2 TFL / 3.5 SACK
Zxavian Harris	DL	37 TKL / 6 TFL / 3 SACK / 1 INT

Florida 2025 Key Players

Name	Position	Stats
Jadan Baugh	RB	747 YDS / 5 TD / 83 YPG / 5 YPC 27 REC / 159 REC YDS / 1 REC TD / 22.7 REC YPG
DJ Lagway	QB	1,762 YDS (64.5%) / 11 TD / 12 INT
Vernell Brown III	WR	33 REC / 485 YDS / 0 TD / 60.6 YPG
Eugene Wilson III	WR	27 REC / 239 YDS / 3 TD / 39.8 YPG
Bryce Thornton	DB	41 TKL / 2 TFL / 1 INT / 1 PD
Kamran James	DL	31 TKL / 3 TFL / 3 SACK
Myles Graham	LB	49 TKL / 3 TFL
Devin Moore	DB	28 TKL / 1 TFL / 1 SACK / 2 INT