Missouri vs. Mississippi State Prediction, Odds, Picks - November 15, 2025

Missouri vs. Mississippi State Prediction, Odds, Picks - November 15, 2025

Updated Nov. 15, 2025 3:04 p.m. ET
FOX Sports

The Missouri Tigers (6-3) are 6.5-point favorites when they host the Mississippi State Bulldogs (5-5) in conference play on Saturday, November 15, 2025 at Memorial Stadium/Faurot Field. The contest has a 51.5-point over/under.

Last time out, the Tigers fell to the Texas A&M Aggies, with 38-17 being the final score. Facing the Georgia Bulldogs in their last game, the Bulldogs lost 41-21.

Keep up with college football all season on FOX Sports.

Missouri vs. Mississippi State Game Information & Odds

  • When: Saturday, November 15, 2025 at 7:45 p.m. ET
  • Location: Memorial Stadium/Faurot Field in Columbia, Missouri
  • TV: SEC Network
  • Live Box Score on FOX Sports
Missouri vs Mississippi State Betting Information updated as of November 15, 2025, 11:46 a.m. ET.
Favorite Spread (Odds) Favorite Moneyline Underdog Moneyline Total Over Moneyline Under Moneyline
Missouri -6.5 (-122) -262 +212 51.5 -110 -110

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Missouri vs. Mississippi State Prediction

  • Pick ATS: Mississippi State (+6.5)
  • Pick OU: Over (51.5)
  • Prediction: Missouri 28, Mississippi State 26

Predictions are made by the Data Skrive betting model.

Learn more about the Missouri Tigers vs. the Mississippi State Bulldogs game on FOX Sports!

Missouri vs. Mississippi State Betting Insights

  • Based on the spread and over/under, the implied score for the matchup is Tigers 29, Bulldogs 22.
  • The Tigers have a 72.4% chance to claim victory in this game based on the moneyline's implied probability. The Bulldogs have a 32.1% implied probability.
  • Missouri has put together a 5-4-0 ATS record so far this year.
  • Mississippi State has compiled an 8-2-0 record against the spread this year.

Missouri vs. Mississippi State: 2025 Stats Comparison

Missouri Mississippi State
Off. Points per Game (Rank) 33.3 (38) 32 (23)
Def. Points per Game (Rank) 19.1 (20) 26.3 (92)
Turnovers Allowed (Rank) 11 (58) 11 (58)
Turnovers Forced (Rank) 8 (109) 15 (33)

Missouri 2025 Key Players

Name Position Stats
Ahmad Hardy RB 1,046 YDS / 12 TD / 116.2 YPG / 6.1 YPC
Beau Pribula QB 1,690 YDS (69.6%) / 11 TD / 7 INT
220 RUSH YDS / 5 RUSH TD / 27.5 RUSH YPG
Jamal Roberts RB 538 YDS / 4 TD / 59.8 YPG / 6.5 YPC
13 REC / 114 REC YDS / 1 REC TD / 14.3 REC YPG
Kevin Coleman Jr. WR 52 REC / 559 YDS / 1 TD / 62.1 YPG
Zion Young DL 28 TKL / 7 TFL / 5 SACK
Josiah Trotter LB 58 TKL / 7 TFL / 1 SACK
Damon Wilson Jr. DL 13 TKL / 5 TFL / 6 SACK / 1 INT
Khalil Jacobs LB 26 TKL / 4 TFL / 3 SACK

Mississippi State 2025 Key Players

Name Position Stats
Blake Shapen QB 2,237 YDS (64.9%) / 15 TD / 6 INT
10 RUSH YDS / 1 RUSH TD / 1 RUSH YPG
Brenen Thompson WR 45 REC / 808 YDS / 6 TD / 80.8 YPG
Davon Booth RB 512 YDS / 7 TD / 51.2 YPG / 4.2 YPC
11 REC / 143 REC YDS / 2 REC TD / 20.4 REC YPG
Da'Marion Bothwell RB 534 YDS / 6 TD / 66.8 YPG / 5.1 YPC
Brylan Lanier DB 51 TKL / 2 TFL / 1 SACK / 3 INT
Jahron Manning DB 69 TKL / 3 TFL / 1 INT / 1 PD
Nic Mitchell LB 57 TKL / 2 TFL / 1.5 SACK
Isaac Smith DB 48 TKL / 1 TFL / 1 SACK / 1 INT

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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