Marshall vs. Appalachian State Prediction, Odds, Picks - November 22, 2025

Updated Nov. 22, 2025 9:04 a.m. ET

Data Skrive

The Marshall Thundering Herd (5-5) are favored by 4.5 points when they hit the road to play the Appalachian State Mountaineers (4-6) in Sun Belt action on Saturday, November 22, 2025 at Kidd Brewer Stadium. The over/under is set at 57 points for the game.

The Thundering Herd won versus the Georgia State Panthers in their most recent game, 30-18. The Mountaineers lost against the James Madison Dukes in their most recent game, 58-10.

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Marshall vs. Appalachian State Game Information & Odds

When: Saturday, November 22, 2025 at 2:30 p.m. ET
Location: Kidd Brewer Stadium in Boone, North Carolina
TV: ESPN+
Live Box Score on FOX Sports

Marshall vs Appalachian State Betting Information updated as of November 22, 2025, 8:45 a.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Marshall	-4.5 (-119)	-216	+177	57	-111	-109

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Marshall vs. Appalachian State Prediction

Pick ATS: Marshall (-4.5)
Pick OU: Over (57)
Prediction: Marshall 34, Appalachian State 28

Predictions are made by the Data Skrive betting model.

Learn more about the Marshall Thundering Herd vs. the Appalachian State Mountaineers game on FOX Sports!

Marshall vs. Appalachian State Betting Insights

Per the spread and over/under, the implied score for the tilt is Thundering Herd 31, Mountaineers 26.
The Thundering Herd have a 68.4% chance to collect the win in this game per the moneyline's implied probability. The Mountaineers hold a 36.1% implied probability.
Marshall is 7-3-0 ATS this season.
Appalachian State has put together a 4-6-0 ATS record so far this year.

Marshall vs. Appalachian State: Head-to-Head

The last four times Appalachian State and Marshall have matched up, the two teams share a split 2-2 record.
In those contests versus Appalachian State, the Thundering Herd have covered three times while going over the point total on three occasions.
In their last four head-to-head matchups, Appalachian State has compiled 120 points versus Marshall, while allowing only 119 points.

Marshall vs. Appalachian State: 2025 Stats Comparison

	Marshall	Appalachian State
Off. Points per Game (Rank)	32.6 (37)	24.9 (93)
Def. Points per Game (Rank)	31.3 (109)	30.4 (104)
Turnovers Allowed (Rank)	11 (43)	17 (111)
Turnovers Forced (Rank)	20 (8)	12 (72)

Marshall 2025 Key Players

Name	Position	Stats
Carlos Del Rio-Wilson	QB	1,761 YDS (68%) / 17 TD / 3 INT 588 RUSH YDS / 4 RUSH TD / 65.3 RUSH YPG
Demarcus Lacey	WR	49 REC / 582 YDS / 5 TD / 64.7 YPG
Michael Allen	RB	353 YDS / 4 TD / 58.8 YPG / 5.5 YPC 11 REC / 135 REC YDS / 1 REC TD / 27 REC YPG
Antwan Roberts	RB	464 YDS / 3 TD / 51.6 YPG / 5.5 YPC
DeWain Trotter	DB	32 TKL / 1 TFL / 0.5 SACK / 5 INT
Cameron Smith	DB	33 TKL / 4 TFL / 2 SACK
Javae Gilmore	LB	39 TKL / 4 TFL / 1.5 SACK
Jabreel Al-Amin	LB	26 TKL / 2 TFL / 3 SACK

Appalachian State 2025 Key Players

Name	Position	Stats
Rashod Dubinion	RB	821 YDS / 4 TD / 82.1 YPG / 5.1 YPC 25 REC / 166 REC YDS / 0 REC TD / 16.6 REC YPG
Jaden Barnes	WR	55 REC / 608 YDS / 7 TD / 60.8 YPG
AJ Swann	QB	1,495 YDS (58.6%) / 10 TD / 8 INT
JJ Kohl	QB	1,060 YDS (58.7%) / 9 TD / 2 INT 32 RUSH YDS / 1 RUSH TD / 8 RUSH YPG
Colton Phares	LB	55 TKL / 5 TFL / 2 SACK / 2 INT
Zyeir Gamble	DB	49 TKL / 2 TFL / 2 INT / 2 PD
Aiden Benton	DL	26 TKL / 2 TFL / 3 SACK
DJ Burks	DB	30 TKL / 1 TFL / 2 INT / 2 PD