Louisville vs. Virginia Tech Prediction, Odds, Picks - November 4

Updated Nov. 4, 2023 3:06 p.m. ET

FOX Sports

The No. 15 Louisville Cardinals (7-1) host the Virginia Tech Hokies (4-4) on Saturday, November 4, 2023 in a matchup between ACC rivals at L&N Federal Credit Union Stadium. Virginia Tech is a 9-point underdog. The point total is 46.5 for the game.

Last time out, the Cardinals defeated the Duke Blue Devils, with 23-0 being the final score. The Hokies' last game was versus the Syracuse Orange, and they won by a score of 38-10.

Louisville vs. Virginia Tech Game Information & Odds

When: Saturday, November 4, 2023 at 3:30 PM ET
Location: L&N Federal Credit Union Stadium in Louisville, Kentucky
TV: ACC Network
Live boxscore on FOX Sports

Louisville vs Virginia Tech Betting Information updated as of November 4, 2023, 2:46 PM ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Louisville	-9 (-110)	-359	+282	46.5	-110	-110

Louisville vs. Virginia Tech Prediction

Pick ATS: Louisville (-9)
Pick OU: Over (46.5)
Prediction: Louisville 32, Virginia Tech 18

Learn more about the Louisville Cardinals vs. the Virginia Tech Hokies game on FOX Sports!

Louisville vs. Virginia Tech Betting Insights

Per the spread and over/under, the implied score for the tilt is Cardinals 28, Hokies 19.
The Cardinals have a 78.2% chance to win this game based on the moneyline's implied probability. The Hokies hold a 26.2% implied probability.
Louisville has won four games against the spread this season, while failing to cover or pushing four times.
Virginia Tech is 5-3-0 ATS this season.

Louisville vs. Virginia Tech: 2023 Stats Comparison

	Louisville	Virginia Tech
Off. Points per Game (Rank)	32.8 (40)	26.1 (83)
Def. Points per Game (Rank)	18.0 (18)	22.9 (46)
Turnovers Allowed (Rank)	11 (64)	8 (24)
Turnovers Forced (Rank)	15 (21)	9 (95)

Louisville 2023 Key Players

Name	Position	Stats
Jawhar Jordan	RB	824 YDS / 10 TD / 103.0 YPG / 7.5 YPC 10 REC / 174 REC YDS / 1 REC TD / 21.8 REC YPG
Jack Plummer	QB	2,018 YDS (63.8%) / 13 TD / 8 INT 32 RUSH YDS / 1 RUSH TD / 4.0 RUSH YPG
Jamari Thrash	WR	46 REC / 712 YDS / 6 TD / 89.0 YPG
Isaac Guerendo	RB	252 YDS / 3 TD / 31.5 YPG / 4.2 YPC 12 REC / 133 REC YDS / 0 REC TD / 16.6 REC YPG
Ashton Gillotte	DL	19 TKL / 7.0 TFL / 7.5 SACK
TJ Quinn	LB	50 TKL / 0.0 TFL
Devin Neal	DB	29 TKL / 0.0 TFL / 3 INT / 3 PD
Ramon Puryear	DL	14 TKL / 3.0 TFL / 2.0 SACK / 1 INT

Virginia Tech 2023 Key Players

Name	Position	Stats
Kyron Drones	QB	1,237 YDS (58.6%) / 7 TD / 1 INT 400 RUSH YDS / 4 RUSH TD / 50.0 RUSH YPG
Bhayshul Tuten	RB	478 YDS / 4 TD / 59.8 YPG / 4.3 YPC 21 REC / 215 REC YDS / 2 REC TD / 26.9 REC YPG
Jaylin Lane	WR	27 REC / 413 YDS / 5 TD / 51.6 YPG
Da'Quan Felton	WR	20 REC / 312 YDS / 4 TD / 39.0 YPG
Antwaun Powell	DL	28 TKL / 8.0 TFL / 9.0 SACK
Keli Lawson	LB	58 TKL / 4.0 TFL / 1.5 SACK / 1 INT
Keonta Jenkins	S	28 TKL / 1.0 TFL / 1.5 SACK / 1 INT
Alan Tisdale	LB	40 TKL / 2.0 TFL / 1.0 SACK