Indiana vs. Alabama Prediction, Odds, Picks - January 1, 2026

Updated Dec. 31, 2025 9:04 a.m. ET

Data Skrive

The College Football Playoff quarterfinal round will see the No. 1 Indiana Hoosiers (13-0) facing the Alabama Crimson Tide (11-3) in the Rose Bowl at 4 p.m. ET in Pasadena, California. Indiana is the favorite in the matchup, by 7 points. The point total is set at 48.5.

The Hoosiers won against the Ohio State Buckeyes in their most recent game, 13-10. The Crimson Tide won against the Oklahoma Sooners in their last game, 34-24.

Keep up with college football all season on FOX Sports.

Indiana vs. Alabama Game Information & Odds

When: Thursday, January 1, 2026 at 4 p.m. ET
Location: Rose Bowl in Pasadena, California
TV: ESPN
Streaming: FOX One + ESPN Bundle

Indiana vs Alabama Betting Information updated as of December 31, 2025, 8:45 a.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Indiana	-7 (-109)	-248	+202	48.5	-106	-119

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Indiana vs. Alabama Prediction

Pick ATS: Indiana (-7)
Pick OU: Over (48.5)
Prediction: Indiana 33, Alabama 17

Predictions are made by the Data Skrive betting model.

Learn more about the Indiana Hoosiers vs. the Alabama Crimson Tide game on FOX Sports!

Indiana vs. Alabama Betting Insights

Per the spread and over/under, the implied score for the tilt is Hoosiers 28, Crimson Tide 21.
The Hoosiers have a 71.3% chance to claim victory in this game based on the moneyline's implied probability. The Crimson Tide hold a 33.1% implied probability.
Indiana has put together an 8-5-0 ATS record so far this year.
Alabama is 9-5-0 ATS this season.

Indiana vs. Alabama: 2025 Stats Comparison

	Indiana	Alabama
Off. Points per Game (Rank)	41.9 (3)	31.4 (19)
Def. Points per Game (Rank)	10.8 (2)	17.9 (25)
Turnovers Allowed (Rank)	8 (3)	12 (18)
Turnovers Forced (Rank)	25 (9)	20 (34)

Indiana 2025 Key Players

Name	Position	Stats
Fernando Mendoza	QB	2,980 YDS (71.5%) / 33 TD / 6 INT 240 RUSH YDS / 6 RUSH TD / 18.5 RUSH YPG
Omar Cooper Jr.	WR	59 REC / 828 YDS / 11 TD / 63.7 YPG
Roman Hemby	RB	918 YDS / 6 TD / 70.6 YPG / 5.2 YPC 14 REC / 160 REC YDS / 0 REC TD / 14.5 REC YPG
Elijah Sarratt	WR	50 REC / 663 YDS / 12 TD / 60.3 YPG
Rolijah Hardy	LB	74 TKL / 11 TFL / 8 SACK
Isaiah Jones	LB	54 TKL / 11 TFL / 7 SACK / 1 INT
Aiden Fisher	LB	62 TKL / 5 TFL / 2.5 SACK / 2 INT
Louis Moore	DB	61 TKL / 2 TFL / 5 INT / 5 PD

Alabama 2025 Key Players

Name	Position	Stats
Ty Simpson	QB	3,500 YDS (64.1%) / 28 TD / 5 INT 76 RUSH YDS / 2 RUSH TD / 5.4 RUSH YPG
Germie Bernard	WR	60 REC / 802 YDS / 7 TD / 61.7 YPG
Isaiah Horton	WR	40 REC / 495 YDS / 8 TD / 38.1 YPG
Daniel Hill	RB	271 YDS / 6 TD / 24.6 YPG / 3.9 YPC 21 REC / 198 REC YDS / 1 REC TD / 24.8 REC YPG
Yhonzae Pierre	LB	40 TKL / 10 TFL / 6.5 SACK
Bray Hubbard	DB	58 TKL / 2 TFL / 1 SACK / 4 INT
Justin Jefferson	LB	67 TKL / 5 TFL / 3 SACK / 1 INT
Deontae Lawson	LB	62 TKL / 1 TFL / 1 SACK