Virginia vs. Northwestern Prediction, How to Watch, Odds, Channel - Nov 21

Updated Nov. 21, 2025 3:27 p.m. ET

Data Skrive

The Virginia Cavaliers (4-0) will look to build on a four-game winning streak when they host the Northwestern Wildcats (4-0) at 5 p.m. ET on Friday, November 21, 2025. The Wildcats have also won four games in a row.

The Cavaliers are a 3.5-point favorite against the Wildcats when the Cavaliers and Wildcats play. The over/under for the matchup is 148.5.

Continue scrolling to get the download ahead of wagering on the Virginia-Northwestern matchup.

Virginia vs. Northwestern How to Watch & Odds

When: Friday, November 21, 2025 at 5 p.m. ET
Where: Colonial Hall in White Sulphur Springs, West Virginia
TV: CBS Sports Network
Live Box Score: FOX Sports

Cavaliers vs Wildcats Betting Information
Favorite	Spread	Favorite Spread Odds	Underdog Spread Odds	Total	Over Total Odds	Under Total Odds	Favorite Moneyline	Underdog Moneyline
Cavaliers	-3.5	-115	-106	148.5	-112	-108	-182	+151

This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports.

Virginia vs. Northwestern Prediction

Pick ATS: Northwestern (+3.5)
Pick OU: Under (148.5)
Prediction: Northwestern 76, Virginia 72

Learn more about the Virginia Cavaliers vs. the Northwestern Wildcats game on FOX Sports!

Virginia vs. Northwestern Betting Insights

Betting Line Implied Predictions

Per the spread and over/under, the implied score for the game is Cavaliers 76, Wildcats 72.
The Cavaliers have a 64.5% chance to claim victory in this meeting per the moneyline's implied probability.
The Wildcats have a 39.8% implied probability to win.

Key Spread Facts

Virginia went 13-19-0 ATS last season.
Northwestern won 17 games against the spread last year, while failing to cover or pushing 16 times.
Virginia was favored by 3.5 points or more nine times last season, and covered the spread in three of those contests.
Northwestern was 7-7 ATS last year when playing as at least a 3.5-point underdog.

Key Total Facts

Six times last year, the Cavaliers and their opponent combined for more than 148.5 points.
There were 10 Wildcats games last year with more than 148.5 points scored.
Last season, the two teams averaged a combined 137.2 points per contest, 11.3 fewer than the total for this matchup.

Key Moneyline Facts

Virginia won nine of the 10 games it was favored on the moneyline last season (90%).
Last season, Northwestern was the underdog 18 times and won four, or 22.2%, of those games.
Virginia had a record of 8-1 when it played as a moneyline favorite with odds of -182 or shorter last year (88.9%).
Last season, Northwestern won one of its 11 games, or 9.1%, when it was the underdog by at least +151 on the moneyline.

Virginia vs. Northwestern: 2024-25 Stats Comparison

	Virginia	Northwestern
Points Scored Per Game (Rank)	64.8 (354)	72.4 (218)
Points Allowed (Rank)	66.8 (39)	69.2 (85)
Rebounds (Rank)	5.8 (356)	9.2 (149)
3pt Made (Rank)	8.3 (111)	6.7 (286)
Assists (Rank)	14.7 (93)	14.5 (105)
Turnovers (Rank)	9.3 (25)	9.3 (25)

Virginia 2024-25 Top Performers

Cavaliers Leaders
Name	GP	PTS	REB	ASST	STL	BLK	3PM
Isaac McKneely	32	14.4	2.7	2.9	0.8	0.1	3.2
Elijah Saunders	29	10.4	5.0	0.8	0.5	0.3	1.1
Andrew Rohde	30	9.3	2.9	4.3	1.2	0.2	1.4
Dai Dai Ames	31	8.7	1.4	1.9	0.8	0.4	1.0
Jacob Cofie	32	7.2	4.6	1.0	1.1	0.8	0.3

Northwestern 2024-25 Top Performers

Wildcats Leaders
Name	GP	PTS	REB	ASST	STL	BLK	3PM
Nick Martinelli	33	20.5	6.2	1.8	0.7	0.2	1.0
Brooks Barnhizer	17	17.1	8.8	4.2	2.3	1.1	1.0
Jalen Leach	23	14.3	2.1	3.4	1.0	0.1	1.7
Ty Berry	33	10.6	3.6	1.3	1.2	0.2	2.2
K.J. Windham	29	5.6	1.1	2.0	0.7	0.1	0.9