USC vs. Oregon Prediction, How to Watch, Odds, Channel - Feb 21

Published Feb. 20, 2026 3:27 p.m. ET

Data Skrive

The Oregon Ducks (9-17, 2-13 Big Ten) will visit the USC Trojans (18-8, 7-8 Big Ten) after losing five straight road games. The contest begins at 4 p.m. ET on Saturday, February 21, 2026.

The Trojans head into their matchup against the Ducks as a 4.5-point favorite. The point total for the game is 144.5.

Keep scrolling to get all the information before wagering on the USC-Oregon matchup.

USC vs. Oregon How to Watch & Odds

When: Saturday, February 21, 2026 at 4 p.m. ET
Where: Galen Center in Los Angeles, California
TV: FS1
Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)

Trojans vs Ducks Betting Information
Favorite	Spread	Favorite Spread Odds	Underdog Spread Odds	Total	Over Total Odds	Under Total Odds	Favorite Moneyline	Underdog Moneyline
Trojans	-4.5	-110	-110	144.5	-118	-104	-230	+188

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USC vs. Oregon Prediction

Pick ATS: USC (-4.5)
Pick OU: Over (144.5)
Prediction: USC 80, Oregon 72

Learn more about the USC Trojans vs. the Oregon Ducks game on FOX Sports!

USC vs. Oregon Betting Insights

Betting Line Implied Predictions

Based on the spread and over/under, the implied score for the game is Trojans 74, Ducks 70.
The Trojans have a 69.7% chance to claim victory in this meeting per the moneyline's implied probability.
The Ducks sit with a 34.7% implied probability to win.

Key Spread Facts

USC has won 13 games against the spread this season, while failing to cover 12 times.
Oregon has put together an 8-18-0 record against the spread this year.
When playing as at least 4.5-point favorites this season, USC has an ATS record of 6-8.
Oregon has covered the spread three times this year (3-7 ATS) when playing as at least 4.5-point underdogs.

Key Total Facts

A total of 18 times so far this season, the Trojans and their opponent have combined to score more than 144.5 points.
Ducks games have gone over 144.5 points on 14 occasions this year.
These two teams score a combined average of 151.9 points per game, higher than the total for this matchup by 7.4 points.

Key Moneyline Facts

USC has won 14 of 16 games when the moneyline favorite this season (87.5%).
This season, Oregon has been listed as the underdog in 13 games and failed to win any of those contests.
USC has gone 12-1 when it has played as a moneyline favorite with odds of -230 or shorter (winning 92.3%).
Oregon has not won as an underdog of +188 or more on the moneyline this season in nine games with those odds or longer.

USC vs. Oregon: Recent Results

Trojans vs Ducks Recent Games
Date	Favorite	Spread	Total	Favorite Moneyline	Underdog Moneyline	Result
12/2/2025	Trojans	-2.5	154.5	-151	+127	82-77 USC
3/1/2025	Ducks	-6.5	152	-319	+255	82-61 ORE
12/4/2024	Ducks	-5.5	148	-253	+205	68-60 ORE

USC vs. Oregon: 2025-26 Stats Comparison

	USC	Oregon
Points Scored Per Game (Rank)	80.7 (84)	71.2 (291)
Points Allowed (Rank)	76.8 (258)	74.3 (196)
Rebounds (Rank)	9.8 (130)	10.2 (89)
3pt Made (Rank)	6.3 (311)	8.1 (153)
Assists (Rank)	15.3 (94)	14.1 (166)
Turnovers (Rank)	12.1 (282)	11.5 (223)

USC 2025-26 Key Players

Trojans Leaders
Name	GP	PTS	REB	ASST	STL	BLK	3PM
Rodney Rice	6	20.3	3.3	6.0	1.2	0.2	2.5
Chad Baker-Mazara	23	18.3	4.2	3.0	0.7	1.3	2.2
Ezra Ausar	26	15.7	6.2	1.8	1.0	0.4	0.0
Alijah Arenas	8	14.5	2.6	1.5	1.0	0.5	1.1
Jacob Cofie	26	10.1	7.1	2.0	1.0	1.6	0.6

Oregon 2025-26 Key Players

Ducks Leaders
Name	GP	PTS	REB	ASST	STL	BLK	3PM
Nathan Bittle	19	16.8	6.7	2.5	0.6	2.1	1.5
Jackson Shelstad	12	15.6	2.9	4.9	1.4	0.1	2.8
Kwame Evans Jr.	24	12.5	7.2	2.2	1.0	1.3	1.0
TK Simpkins	25	12.4	2.9	2.1	1.0	0.2	1.8
Sean Stewart	26	7.0	5.4	1.0	0.9	0.5	0.0